Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214271 | 0.85 | PKM (0.38) | CA12CA1CA2CA9SLC6A3 | |
| SCHEMBL11213627 | 0.81 | MT-CO2 (0.43) | MT-CO2PTGS1PTGS2CA12CA1 | |
| SCHEMBL10931210 | 0.79 | MT-CO2 (0.47) | MT-CO2PTGS1PTGS2SLC6A3AKR1C2 | |
| SCHEMBL29749568 | 0.79 | MT-CO2 (0.47) | MT-CO2PTGS1PTGS2SLC6A3AKR1C2 | |
| SCHEMBL24132878 | 0.78 | MT-CO2 (0.48) | MT-CO2PTGS1PTGS2CA12CA1 | |
| SCHEMBL11219168 | 0.75 | GABRA1 (0.42) | MT-CO2PTGS1PTGS2CA12CA1 | |
| SCHEMBL11216724 | 0.74 | ALDH1A1 (0.58) | MT-CO2PTGS1PTGS2ALOX15ALOX12 | |
| SCHEMBL31430560 | 0.74 | ALDH1A1 (0.58) | MT-CO2PTGS1PTGS2ALOX15ALOX12 | |
| SCHEMBL17891807 | 0.74 | MT-CO2 (0.55) | MT-CO2PTGS1PTGS2CA2SLC6A3 | |
| SCHEMBL1626214 | 0.73 | SLC6A3 (0.57) | MT-CO2PTGS1PTGS2SLC6A3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0081321-A1 | 2-Aminophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-06-15 | — | — | EP | disclosed |