SCHEMBL11213752

SCHEMBL11213752

Cc1cc(N=O)cc(Cl)c1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.40
TXNRD1 Q16881 1/20 0.39
TXNRD3 Q86VQ6 1/20 0.39
TXNRD2 Q9NNW7 1/20 0.39
ALDH1A1 P00352 2/20 0.38
HSD17B10 Q99714 2/20 0.38
GAA P10253 1/20 0.38
PKM P14618 1/20 0.38
ALOX15 P16050 1/20 0.38
HTT P42858 1/20 0.38
HTR3E A5X5Y0 1/20 0.36
HTR3B O95264 1/20 0.36
HTR3A P46098 1/20 0.36
HTR3D Q70Z44 1/20 0.36
HTR3C Q8WXA8 1/20 0.36
TTR P02766 2/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL836394 0.84 CA1 (0.50) BRD4ALDH1A1HSD17B10GAATTR
SCHEMBL28174120 0.77 BRD4 (0.38) BRD4ALDH1A1HSD17B10GAAHTT
SCHEMBL24594962 0.75 GRIN2D (0.34) ALDH1A1HSD17B10HTR3EHTR3BHTR3A
SCHEMBL295740 0.74 MCL1 (0.38) ALDH1A1HSD17B10PKMALOX15HTR3E
SCHEMBL14256816 0.74 HTR3E (0.50) ALDH1A1HSD17B10PKMHTTHTR3E
SCHEMBL19625967 0.73 SHBG (0.37) BRD4ALDH1A1GAAMEN1MAPT
SCHEMBL3668597 0.72 CYP2C9 (0.57) ALDH1A1HSD17B10GAAALOX15HTT
SCHEMBL22083841 0.71 CYP3A4 (0.45) ALDH1A1HSD17B10GAAHTTMAPT
SCHEMBL30804415 0.70 ALDH1A1 (0.65) ALDH1A1HSD17B10ALOX15HTTTTR
SCHEMBL1893469 0.70 ALDH1A1 (0.65) ALDH1A1HSD17B10ALOX15HTTTTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0020065-B1 A METHOD FOR INHIBITING THE POLYMERIZATION OF ACRYLIC MONOMERS IN AQUEOUS LIQUIDS CONTAINING THEM ROHM AND HAAS COMPANY (US) 1983-02-23 EP disclosed
EP-0020065-A1 A method for inhibiting the polymerization of acrylic monomers in aqueous liquids containing them ROHM AND HAAS COMPANY (US) 1980-12-10 EP disclosed