Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214293 | 0.78 | HTR1A (0.56) | ALDH1A1LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL27717491 | 0.77 | MEN1 (0.67) | ALDH1A1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL15539821 | 0.76 | SLC6A9 (0.60) | ALDH1A1MEN1KMT2ASLC6A9HTR1A | |
| SCHEMBL31537013 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MCOLN3NOTUMLMNANR1H4 | |
| SCHEMBL4152763 | 0.73 | SLC6A9 (0.67) | ALDH1A1SMN1; SMN2SLC6A9HTR1AADRA1A | |
| SCHEMBL11211339 | 0.72 | ATM (0.53) | ALDH1A1MCOLN3LMNA | |
| SCHEMBL2070458 | 0.72 | NOTUM (0.83) | NOTUMLMNANR1H4 | |
| Hydrochloric Acid SCHEMBL4152568 | 0.72 | SLC6A9 (0.65) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11214631 | 0.71 | ADRA1B (0.61) | NOTUMLMNAADRA1BHTR1AADRA1A | |
| SCHEMBL11955709 | 0.71 | NPSR1 (0.59) | ALDH1A1MCOLN3LMNANR1H4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325952-A | Method of treating abstinence syndrome with cycloaklyltriazoles | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO (IT) | 1982-04-20 | — | — | US | disclosed |
| US-4307095-A | PSYCHOTHERAPY AND ANTIGLAUCOMA AGENTS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 1981-12-22 | — | — | US | disclosed |
| US-4307096-A | Method of treating glaucoma with cycloalkyltriazoles | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 1981-12-22 | — | — | US | disclosed |
| US-4252721-A | ANTIGLAUCOMIC AND ANTIPSYCHOTIC AGENTS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 1981-02-24 | — | — | US | disclosed |