Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 10/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6170258 | 0.80 | ALDH1A1 (0.34) | PARP1TDP1RECQLALDH1A1CYP3A4 | |
| SCHEMBL28424460 | 0.65 | PARP1 (0.47) | PARP1TDP1RECQLALDH1A1CYP3A4 | |
| SCHEMBL11568940 | 0.61 | S100A4 (0.33) | PARP1TDP1ALDH1A1CYP3A4HPGD | |
| SCHEMBL21854609 | 0.61 | ALDH1A1 (0.87) | PARP1TDP1RECQLALDH1A1CYP3A4 | |
| SCHEMBL29365003 | 0.61 | ALDH1A1 (1.00) | PARP1TDP1RECQLALDH1A1CYP3A4 | |
| SCHEMBL48843 | 0.61 | ALDH1A1 (1.00) | PARP1TDP1RECQLALDH1A1CYP3A4 | |
| SCHEMBL27912581 | 0.61 | ALDH1A1 (1.00) | PARP1TDP1RECQLALDH1A1CYP3A4 | |
| SCHEMBL840996 | 0.60 | DNMT1 (0.35) | PARP1 | |
| SCHEMBL9039648 | 0.60 | C1R (0.36) | PARP1POLBKDM4EGAA | |
| SCHEMBL1286271 | 0.60 | ALDH1A1 (0.52) | PARP1TDP1RECQLALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-52151176-A | — | — | None | — | — | JP | disclosed |
| US-4373087-A | P-PHENYLENEDIAMINE, TEREPHTHALIC ACID | UBE INDUSTRIES LTD. (JP) | 1983-02-08 | — | — | US | disclosed |
| US-4178431-A | HEAT RESISTANCE, REINFORCERS FOR PLASTICS AND RUBBERS | UBE INDUSTRIES, LTD. (JP) | 1979-12-11 | — | — | US | disclosed |
| US-4178431-A | HEAT RESISTANCE, REINFORCERS FOR PLASTICS AND RUBBERS | UBE INDUSTRIES, LTD. (JP) | 1979-12-11 | — | — | US | disclosed |
| JP-S52151176-A | PREPARATION OF 2,7-DIAMINOPHENANTHRIDONE | UBE IND LTD | 1977-12-15 | — | — | JP | disclosed |