Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 5/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FGR | P09769 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568940 | 0.81 | S100A4 (0.33) | ALDH1A1CYP3A4HPGDTSHRKEAP1 | |
| SCHEMBL9039648 | 0.80 | C1R (0.36) | PARP1CSNK2A2CSNK2BCSNK2A1POLB | |
| SCHEMBL11773632 | 0.80 | ALOX5 (0.38) | ALDH1A1HPGDHSD17B10PARP1CSNK2A2 | |
| SCHEMBL11214964 | 0.80 | PARP1 (0.42) | ALDH1A1CYP3A4HPGDTSHRKEAP1 | |
| SCHEMBL840996 | 0.80 | DNMT1 (0.35) | PARP1CSNK2A2CSNK2BCSNK2A1DNMT1 | |
| SCHEMBL5312559 | 0.79 | PARP1 (0.33) | ALDH1A1HSD17B10PARP1TDP1CSNK2A2 | |
| SCHEMBL3327474 | 0.78 | PARP1 (0.45) | ALDH1A1HPGDPARP1TDP1CSNK2A2 | |
| SCHEMBL9020742 | 0.76 | ELANE (0.32) | ALDH1A1HSD17B10PARP1TDP1CSNK2A2 | |
| SCHEMBL378547 | 0.74 | DNMT1 (0.38) | ALDH1A1HSD17B10PARP1TDP1CSNK2A2 | |
| Hydrochloric Acid SCHEMBL28299257 | 0.72 | DNMT1 (0.37) | ALDH1A1HSD17B10PARP1TDP1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6958347-B2 | Aminophenanthridinone and aminophenanthridine as NPY-5 antagonists | PFIZER INC. (US) | 2005-10-25 | — | — | US | disclosed |
| US-6958347-B2 | Aminophenanthridinone and aminophenanthridine as NPY-5 antagonists | PFIZER INC. (US) | 2005-10-25 | — | — | US | disclosed |
| EP-1578728-A1 | 5-AMINOPHENANTHRIDINE DERIVATIVES AS NPY-5 ANTAGONISTS | Pfizer Products Inc. (US) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004054981-A1 | 5-AMINOPHENANTHRIDINE DERIVATIVES AS NPY-5 ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2004-07-01 | — | — | WO | disclosed |
| US-20040122038-A1 | NPY-5 antagonists | PFIZER INC | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122038-A1 | NPY-5 antagonists | NPY5R, NPY1R, NPY2R | ALDH1A1 2832/4885CYP3A4 3008/4885HPGD 1033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.