Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 2/20 | 0.33 |
| ▸ | TTK | P33981 | 2/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.33 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6170258 | 0.81 | ALDH1A1 (0.34) | S100A4AURKATTKAURKBINCENP | |
| SCHEMBL7820822 | 0.74 | ALDH1A1 (0.39) | PARP1ALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL457598 | 0.73 | KDM4E (0.39) | PARP1ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL11773632 | 0.71 | ALOX5 (0.38) | MAPTPARP1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9039648 | 0.71 | C1R (0.36) | PARP1CSNK2A2CSNK2BCSNK2A1GAA | |
| SCHEMBL840996 | 0.71 | DNMT1 (0.35) | PARP1CSNK2A2CSNK2BCSNK2A1CES1 | |
| SCHEMBL5312559 | 0.70 | PARP1 (0.33) | PARP1ALDH1A1HSD17B10CSNK2A2CSNK2B | |
| SCHEMBL11584814 | 0.70 | CYP3A4 (0.44) | S100A4MAPTPARP1ALDH1A1CYP3A4 | |
| SCHEMBL3327474 | 0.69 | PARP1 (0.45) | MAPTPARP1ALDH1A1HPGDCSNK2A2 | |
| SCHEMBL378547 | 0.68 | DNMT1 (0.38) | MAPTPARP1ALDH1A1HSD17B10CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178431-A | HEAT RESISTANCE, REINFORCERS FOR PLASTICS AND RUBBERS | UBE INDUSTRIES, LTD. (JP) | 1979-12-11 | — | — | US | disclosed |