Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
| ▸ | PRKACG | P22612 | 1/20 | 0.30 |
| ▸ | PRKACB | P22694 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.30 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.30 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11773632 | 0.80 | ALOX5 (0.38) | PARP1CES1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6170258 | 0.80 | ALDH1A1 (0.34) | DNMT1PARP1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL9039648 | 0.80 | C1R (0.36) | DNMT1PARP1CES1CSNK2A2CSNK2B | |
| SCHEMBL5312559 | 0.79 | PARP1 (0.33) | DNMT1PARP1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3327474 | 0.78 | PARP1 (0.45) | DNMT1PARP1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL9020742 | 0.76 | ELANE (0.32) | PARP1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL378547 | 0.74 | DNMT1 (0.38) | DNMT1PARP1CES1CSNK2A2CSNK2B | |
| Hydrochloric Acid SCHEMBL6554454 | 0.72 | DNMT1 (0.37) | DNMT1PARP1CES1CSNK2A2CSNK2B | |
| Hydrochloric Acid SCHEMBL28299257 | 0.72 | DNMT1 (0.37) | DNMT1PARP1CES1CSNK2A2CSNK2B | |
| SCHEMBL11568940 | 0.71 | S100A4 (0.33) | DNMT1PARP1CES1CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3569606-B1 | METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF | UNIVERSAL DISPLAY CORP (US) | 2022-01-05 | — | — | EP | disclosed |
| US-10978649-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2021-04-13 | — | — | US | disclosed |
| US-20200350504-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2020-11-05 | — | — | US | disclosed |
| US-10749121-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2020-08-18 | — | — | US | disclosed |
| EP-3569606-A1 | METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF | Universal Display Corporation (US) | 2019-11-20 | — | — | EP | disclosed |
| US-20190341563-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2019-11-07 | — | — | US | disclosed |
| US-10403831-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2019-09-03 | — | — | US | disclosed |
| EP-2399922-B1 | Metal complexes of cyclometallated imidazo(1,2-f) phenanthridine and diimidazo(1,2-A;1',2'-C)quinazoline ligands and isoelectronic and benzannulated analogs therof | UNIVERSAL DISPLAY CORP (US) | 2019-06-26 | — | — | EP | disclosed |
| EP-1981898-B2 | Metal complexes of imidazo[1,2-f]phenanthridine ligands for use in OLED devices | UNIVERSAL DISPLAY CORP (US) | 2019-04-10 | — | — | EP | disclosed |
| US-20190058138-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2019-02-21 | — | — | US | disclosed |
| US-5336674-A | Grampositive bacteria, particularly methicillin-resistant Staphylococcus | MERCK & CO., INC. (US) | 1994-08-09 | — | — | US | disclosed |
| WO-1994017066-A1 | 2-PHENANTHRIDINYL CARBAPENEM ANTIBACTERIAL AGENTS | MERCK & CO., INC. (US) | 1994-08-04 | — | — | WO | disclosed |
| WO-1994017065-A1 | 2-PHENANTHRIDINYL CARBAPENEM ANTIBACTERIAL AGENTS | MERCK & CO., INC. (US) | 1994-08-04 | — | — | WO | disclosed |
| US-5328904-A | Active against methicillin resistant Staphylococcus | MERCK & CO., INC. (US) | 1994-07-12 | — | — | US | disclosed |
| US-5214139-A | 2-phenanthridonyl-carbapenems | MERCK & CO., INC. (US) | 1993-05-25 | — | — | US | disclosed |
| US-5208328-A | Intermediates for antibiotics and bactericides | MERCK & CO., INC. (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0509780-A1 | 2-phenanthridonyl carbapenems | MERCK & CO. INC. (US) | 1992-10-21 | — | — | EP | disclosed |
| EP-0509756-A1 | 2-Phenanthridonyl carbapenems having cationizeable substituents | MERCK & CO. INC. (US) | 1992-10-21 | — | — | EP | disclosed |
| US-5157033-A | Controlling methicillin-resistant grampositive Staphylococcus; bactericides | MERCK & CO., INC. (US) | 1992-10-20 | — | — | US | disclosed |
| US-5153185-A | Antibiotics for methicillin resistant Staphylococcus strains | MERCK & CO., INC. (US) | 1992-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190341563-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | LIG1, L1CAM, LIG3 | DNMT1 169/4885PARP1 206/4885CES1 4575/4885 |
| US-20190058138-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | LIG1, L1CAM, LIG3 | DNMT1 169/4885PARP1 206/4885CES1 4575/4885 |
| US-10978649-B2 | Organic electroluminescent materials and devices | NR2C2, NR2E3, NCOA2 | DNMT1 700/4885PARP1 2696/4885CES1 3076/4885 |
| US-10749121-B2 | Organic electroluminescent materials and devices | LIG1, L1CAM, LIG3 | DNMT1 169/4885PARP1 206/4885CES1 4575/4885 |
| US-10403831-B2 | Organic electroluminescent materials and devices | LIG1, L1CAM, LIG3 | DNMT1 169/4885PARP1 206/4885CES1 4575/4885 |
| US-20200350504-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | NR2C2, NR2E3, NCOA2 | DNMT1 700/4885PARP1 2696/4885CES1 3076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.