Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11210871 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1HTTLMNAFFAR4 | |
| SCHEMBL36774 | 0.80 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1HTTLMNAFFAR4 | |
| SCHEMBL7149973 | 0.80 | FFAR1 (0.59) | SMN1; SMN2ALDH1A1HTTLMNAFFAR1 | |
| SCHEMBL11212638 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1HTTLMNAFFAR4 | |
| SCHEMBL10989690 | 0.75 | TSHR (0.47) | SMN1; SMN2ALDH1A1HTTLMNAFFAR4 | |
| SCHEMBL6681003 | 0.74 | SOS1 (0.63) | SMN1; SMN2ALDH1A1HTTLMNAFFAR4 | |
| SCHEMBL10353056 | 0.73 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1HTTLMNAPKM | |
| SCHEMBL3004495 | 0.73 | HTT (0.49) | SMN1; SMN2ALDH1A1HTTLMNAPKM | |
| SCHEMBL1864223 | 0.73 | LMNA (0.55) | SMN1; SMN2ALDH1A1HTTLMNAPKM | |
| SCHEMBL419059 | 0.73 | CA1 (0.66) | SMN1; SMN2ALDH1A1LMNAFFAR4GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030333-B1 | ALKYLDIPHENYL-ETHER SULFONIC ACID HYDRAZIDES, THEIR PRODUCTION AND USE AS BLOWING AGENTS | BAYER AG (DE) | 1983-03-09 | — | — | EP | disclosed |
| US-4329499-A | Alkyldiphenyl ether-sulphonic acid hydrazides, their preparation and their use as blowing agents | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-11 | — | — | US | disclosed |
| EP-0030333-A1 | Alkyldiphenyl-ether sulfonic acid hydrazides, their production and use as blowing agents | BAYER AG (DE) | 1981-06-17 | — | — | EP | disclosed |