⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221601 | 0.74 | SIGMAR1 (0.32) | — | |
| SCHEMBL9278813 | 0.73 | — | — | |
| SCHEMBL7913464 | 0.69 | ALDH1A1 (0.43) | — | |
| SCHEMBL11191674 | 0.67 | — | — | |
| SCHEMBL10652425 | 0.67 | — | — | |
| SCHEMBL9633919 | 0.65 | OPRM1 (0.32) | — | |
| SCHEMBL11196936 | 0.63 | — | — | |
| SCHEMBL11765817 | 0.62 | OGA (0.53) | — | |
| SCHEMBL7342049 | 0.60 | CARM1 (0.46) | — | |
| SCHEMBL12475877 | 0.60 | POLB (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085291-A1 | 2-Oxo-1-(aminocarbonylaminosulfonylaminocarbonyl)azetidines | E.R. Squibb & Sons, Inc. (US) | 1983-08-10 | — | — | EP | disclosed |