Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.53 |
| ▸ | HEXA | P06865 | 1/20 | 0.53 |
| ▸ | HEXB | P07686 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.49 |
| ▸ | GLS | O94925 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28895602 | 0.90 | ACHE (0.55) | SIRT1ACHE | |
| SCHEMBL805142 | 0.84 | OGA (0.70) | OGAHEXAHEXBCASP3SIRT1 | |
| SCHEMBL7973833 | 0.82 | OGA (0.68) | OGAHEXAHEXBCASP3SIRT1 | |
| SCHEMBL20818051 | 0.78 | ALDH1A1 (0.59) | OGAHEXAHEXBSIRT1GLS | |
| SCHEMBL21852149 | 0.77 | ACHE (0.54) | OGAHEXAHEXBSIRT1GLS | |
| SCHEMBL1210939 | 0.77 | OGA (0.57) | OGAHEXAHEXBSIRT1GLS | |
| SCHEMBL7476248 | 0.77 | SIRT1 (0.66) | OGAHEXAHEXBSIRT1ACHE | |
| SCHEMBL29419302 | 0.77 | CASP3 (0.58) | CASP3GLSPOLBNPSR1ALDH1A1 | |
| SCHEMBL369820 | 0.77 | CASP3 (0.58) | CASP3GLSPOLBNPSR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31238051 | 0.76 | TERT (0.50) | SIRT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484502-B | Artemisinin derivative and intermediate, preparation method and application thereof | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2022-07-26 | — | — | CN | disclosed |
| CN-111484502-A | Artemisinin derivative and intermediate, preparation method and application thereof | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2020-08-04 | — | — | CN | disclosed |
| US-4010180-A | Process for the purification of copper phthalocyanine | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-01 | — | — | US | disclosed |