Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760125 | 0.81 | CASP6 (0.62) | CASP6MAPTLMNAHTTNPSR1 | |
| SCHEMBL11654108 | 0.81 | CASP6 (0.67) | CASP6MAPTLMNAHTTNPSR1 | |
| SCHEMBL16324795 | 0.79 | ALDH1A1 (0.67) | CASP6MAPTLMNAHTTNPSR1 | |
| SCHEMBL8302813 | 0.79 | SMN1; SMN2 (0.60) | CASP6MAPTLMNAHTTCYP1A2 | |
| SCHEMBL11191042 | 0.79 | ALDH1A1 (0.56) | CASP6MAPTLMNAHTTALDH1A1 | |
| SCHEMBL1524805 | 0.78 | MAPT (0.62) | MAPTLMNAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL22734863 | 0.78 | CASP6 (0.62) | CASP6MAPTLMNAHTTNPSR1 | |
| SCHEMBL20982472 | 0.78 | SMN1; SMN2 (0.65) | CASP6MAPTLMNAHTTNPSR1 | |
| SCHEMBL8026418 | 0.76 | ALDH1A1 (0.64) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL20982693 | 0.76 | PRMT5 (0.60) | CASP6MAPTLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0092830-A2 | Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their application | CIBA-GEIGY AG (CH) | 1983-11-02 | — | — | EP | claimed |
| EP-0092830-A2 | Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their application | CIBA-GEIGY AG (CH) | 1983-11-02 | — | — | EP | disclosed |