Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 17/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31518544 | 0.85 | L3MBTL1 (0.49) | CMA1NOTUM | |
| SCHEMBL27604349 | 0.74 | TNKS (0.40) | CMA1NOTUM | |
| SCHEMBL11216231 | 0.73 | CYP3A4 (0.34) | CMA1 | |
| SCHEMBL2409298 | 0.72 | TSHR (0.52) | TSHRNOTUM | |
| SCHEMBL31518571 | 0.71 | SMN1; SMN2 (0.53) | TSHR | |
| SCHEMBL4457378 | 0.71 | THRB (0.43) | — | |
| SCHEMBL1962849 | 0.71 | ALDH1A1 (0.60) | CMA1TSHRPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL30444472 | 0.71 | ALDH1A1 (0.60) | CMA1TSHRPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL8147731 | 0.71 | NPC1 (0.36) | NOTUM | |
| SCHEMBL14899249 | 0.70 | GAA (0.42) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072405-A | Heterocyclic monoacylglycerol lipase (MAGL) inhibitors | 豪夫迈·罗氏有限公司 | 2022-02-18 | — | — | CN | disclosed |