Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 6/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | ASIC1 | P78348 | 1/20 | 0.32 |
| ▸ | BCKDK | O14874 | 2/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10584615 | 0.86 | ASIC3 (0.41) | ASIC3LOXL2MIFTBXAS1ASIC1 | |
| SCHEMBL10855114 | 0.81 | ASIC3 (0.40) | ASIC3LOXL2MIFTBXAS1ASIC1 | |
| SCHEMBL10859530 | 0.71 | TBXAS1 (0.33) | MIFTBXAS1 | |
| SCHEMBL10855358 | 0.70 | TBXAS1 (0.67) | TBXAS1 | |
| SCHEMBL10855374 | 0.70 | TAAR1 (0.40) | ASIC3LOXL2MIFTBXAS1 | |
| SCHEMBL29670038 | 0.69 | RPA1 (0.36) | MIFBCKDKMCL1RXFP1BCL2L1 | |
| SCHEMBL28770285 | 0.69 | RPA1 (0.36) | MIFBCKDKMCL1RXFP1BCL2L1 | |
| SCHEMBL205544 | 0.69 | RAB9A (0.41) | MIF | |
| SCHEMBL29644557 | 0.69 | RAB9A (0.41) | MIF | |
| SCHEMBL30406558 | 0.67 | MIF (0.46) | MIFBCKDKMCL1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073663-A2 | Thromboxane synthetase inhibitors, processes for their production, and pharmaceutical compositions comprising them | Pfizer Limited (GB) | 1983-03-09 | — | — | EP | disclosed |