Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 12/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2705467 | 0.86 | ALDH1A1 (0.59) | CES2CES1MAPK14MAPK13MAPK12 | |
| SCHEMBL2703087 | 0.84 | KEAP1 (0.59) | CES2CES1MAPK14MAPK13MAPK12 | |
| SCHEMBL5282720 | 0.83 | MAPT (0.59) | CES2CES1MAPTGAAALDH1A1 | |
| SCHEMBL29664874 | 0.83 | MAPT (0.59) | CES2CES1MAPTGAAALDH1A1 | |
| SCHEMBL4095495 | 0.83 | MAPT (0.47) | CES2CES1MAPK14MAPK13MAPK12 | |
| SCHEMBL13291390 | 0.83 | CES2 (0.74) | CES2CES1MAPK14MAPK13MAPK12 | |
| SCHEMBL28305665 | 0.82 | ALDH1A1 (0.49) | CES2CES1MAPK14MAPK13MAPK12 | |
| SCHEMBL2704610 | 0.82 | RECQL (0.58) | CES2CES1MAPK14MAPK13MAPK12 | |
| SCHEMBL8864704 | 0.81 | ALDH1A1 (0.55) | CES2CES1MAPK14MAPK13MAPK12 | |
| SCHEMBL9539537 | 0.80 | MAPK14 (0.47) | CES2CES1MAPK14MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313949-A | Method of producing an inhibitory effect on blood platelet aggregation | A. H. ROBINS COMPANY, INC. (US) | 1982-02-02 | — | — | US | disclosed |