Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | DRD2 | P14416 | 3/20 | 0.69 |
| ▸ | DRD1 | P21728 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | DRD4 | P21917 | 2/20 | 0.69 |
| ▸ | DRD5 | P21918 | 2/20 | 0.69 |
| ▸ | DRD3 | P35462 | 2/20 | 0.69 |
| ▸ | RECQL | P46063 | 2/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | HTR1A | P08908 | 2/20 | 0.69 |
| ▸ | APEX1 | P27695 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31484728 | 0.89 | ALDH1A1 (0.53) | TAAR1MAPK1DRD2DRD1KDM4E | |
| SCHEMBL9008919 | 0.89 | ALDH1A1 (0.53) | TAAR1MAPK1DRD2DRD1KDM4E | |
| SCHEMBL272900 | 0.84 | ALOX15 (0.58) | TAAR1MAPK1DRD2DRD1KDM4E | |
| SCHEMBL11004150 | 0.83 | ALOX15 (0.61) | TAAR1MAPK1DRD2DRD1KDM4E | |
| SCHEMBL11004234 | 0.83 | ALOX15 (0.61) | TAAR1MAPK1DRD2DRD1KDM4E | |
| SCHEMBL18928227 | 0.83 | ALDH1A1 (0.65) | TAAR1MAPK1DRD2DRD1KDM4E | |
| SCHEMBL10409135 | 0.83 | TAAR1 (0.69) | TAAR1MAPK1DRD2DRD1KDM4E | |
| Dopamine SCHEMBL9166387 | 0.82 | KDM4E (1.00) | TAAR1MAPK1DRD2DRD1KDM4E | |
| Dopamine SCHEMBL18159501 | 0.82 | KDM4E (1.00) | TAAR1MAPK1DRD2DRD1KDM4E | |
| Dopamine SCHEMBL8505 | 0.82 | KDM4E (1.00) | TAAR1MAPK1DRD2DRD1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119591621-A | Novel ecteinascidin derivatives, preparation method and application thereof, antibody drug conjugate and application thereof | 泰诚思(上海)生物医药有限公司 | 2025-03-11 | — | — | CN | disclosed |
| WO-2023143563-A1 | IGA PROTEASE TRUNCATION, FUSION PROTEIN COMPRISING IGA PROTEASE TRUNCATION, AND USE THEREOF | 北京大学第一医院 | 2023-08-03 | — | — | WO | disclosed |
| EP-3330252-A2 | ISOPRENYL COMPOUNDS AND METHODS THEREOF | Signum Biosciences, Inc. (US) | 2018-06-06 | — | — | EP | disclosed |
| US-9560848-B2 | Method and compositions for biofouling deterrence | CLEMSON UNIVERSITY (US) | 2017-02-07 | — | — | US | disclosed |
| EP-2176243-B1 | OPHTHALMIC LENS MATERIALS CONTAINING CHROMOPHORES THAT ABSORB BOTH UV AND SHORT WAVELENGTH VISIBLE LIGHT | ALCON INC (CH) | 2011-02-09 | — | — | EP | disclosed |
| EP-2176243-B1 | OPHTHALMIC LENS MATERIALS CONTAINING CHROMOPHORES THAT ABSORB BOTH UV AND SHORT WAVELENGTH VISIBLE LIGHT | ALCON INC (CH) | 2011-02-09 | — | — | EP | disclosed |
| US-7728051-B2 | Ophthalmic lens materials containing chromophores that absorb both UV and short wavelength visible light | ALCON, INC. (CH) | 2010-06-01 | — | — | US | disclosed |
| US-7728051-B2 | Ophthalmic lens materials containing chromophores that absorb both UV and short wavelength visible light | ALCON, INC. (CH) | 2010-06-01 | — | — | US | disclosed |
| US-7728051-B2 | Ophthalmic lens materials containing chromophores that absorb both UV and short wavelength visible light | ALCON, INC. (CH) | 2010-06-01 | — | — | US | disclosed |
| EP-2176243-A1 | OPHTHALMIC LENS MATERIALS CONTAINING CHROMOPHORES THAT ABSORB BOTH UV AND SHORT WAVELENGTH VISIBLE LIGHT | Alcon, Inc. (CH) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009021085-A1 | OPHTHALMIC LENS MATERIALS CONTAINING CHROMOPHORES THAT ABSORB BOTH UV AND SHORT WAVELENGTH VISIBLE LIGHT | ALCON, INC. (CH) | 2009-02-12 | — | — | WO | disclosed |
| EP-0477501-A2 | Apparatus for continuously monitoring a plurality of chemical analytes through a single optical fiber and method of making | ABBOTT LABORATORIES (US) | 1992-04-01 | — | — | EP | disclosed |
| US-5098659-A | APPARATUS FOR CONTINUOUSLY MONITORING A PLURALITY OF CHEMICAL ANALYTES THROUGH A SINGLE OPTICAL FIBER AND METHOD OF MAKING | ABBOTT LABORATORIES (US) | 1992-03-24 | — | — | US | disclosed |
| US-5093355-A | Hypotensive agents, cardiovascular disorders, renal failure | SYNTEX (U.S.A.) INC. (US) | 1992-03-03 | — | — | US | disclosed |
| EP-0457292-A2 | Improved configuration fiber-optic blood gas sensor bundle and method of making | ABBOTT LABORATORIES (US) | 1991-11-21 | — | — | EP | disclosed |
| US-5047627-A | Configuration fiber-optic blood gas sensor bundle and method of making | ABBOTT LABORATORIES (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0404115-A1 | Bis(benzylpyrrolidine)Derivatives as dopamine agonists | SYNTEX (U.S.A.) INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4958026-A | HYPOTENSIVE AGENTS | SCHERING AKTIENGESLLSCHAFT (DE) | 1990-09-18 | — | — | US | disclosed |
| EP-0189473-A1 | NEW DOPAMINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE AS MEDICINAL PRODUCTS. | SCHERING AG (DE) | 1986-08-06 | — | — | EP | disclosed |
| WO-1986001204-A1 | NEW DOPAMINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE AS MEDICINAL PRODUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-02-27 | — | — | WO | disclosed |