Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 6/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SCN1A | P35498 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14477157 | 0.89 | NR2E1 (0.60) | NR2E1CYP1A2KDM4EMEN1CYP2C19 | |
| SCHEMBL9336777 | 0.79 | HTR1B (0.50) | CYP1A2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL19683357 | 0.78 | NR2E1 (0.44) | NR2E1CYP1A2KDM4EMEN1CYP2C19 | |
| SCHEMBL6663577 | 0.78 | ALOX15 (0.53) | CYP1A2KDM4ECYP2C19CYP2D6ALDH1A1 | |
| SCHEMBL31040026 | 0.77 | LMNA (0.45) | CYP1A2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL28273569 | 0.77 | L3MBTL1 (0.39) | CYP1A2KDM4EMEN1KMT2ASLC6A4 | |
| SCHEMBL7694021 | 0.76 | KMT2A (0.49) | CYP1A2MEN1CYP2C19KMT2AALDH1A1 | |
| SCHEMBL31345547 | 0.76 | CYP1A2 (0.40) | NR2E1CYP1A2KDM4EADRB2ADRB1 | |
| SCHEMBL31040058 | 0.74 | L3MBTL1 (0.37) | NR2E1CYP1A2KDM4EMEN1KMT2A | |
| SCHEMBL19683548 | 0.74 | NR2E1 (0.40) | NR2E1CYP1A2KDM4EMEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844375-B2 | 4-methylene-1,3-dioxolanes as cross-linking agents | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-01-18 | — | — | US | disclosed |
| EP-1182201-B1 | 4-Methylene-1,3-dioxolanes as cross-linking agents | DAINIPPON INK & CHEMICALS (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-20020045674-A1 | 4-Methylene-1,3-dioxolanes as cross-linking agents | DAINIPPON INK AND CHEMICALS, INC (JP) | 2002-04-18 | — | — | US | disclosed |
| EP-1182201-A1 | 4-Methylene-1,3-dioxolanes as cross-linking agents | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045674-A1 | 4-Methylene-1,3-dioxolanes as cross-linking agents | COL1A1, CCNA1, GJA1 | NR2E1 841/4885CYP1A2 132/4885KDM4E 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.