Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6871413 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TSHRNPSR1L3MBTL1METAP2 | |
| SCHEMBL11218222 | 0.79 | CPB2 (0.33) | ALDH1A1TSHRMAPT | |
| SCHEMBL11024454 | 0.79 | METAP2 (0.45) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL11655565 | 0.78 | TDP1 (0.56) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL11020183 | 0.77 | METAP2 (0.44) | TSHRTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11024026 | 0.77 | METAP2 (0.47) | ALDH1A1TDP1MEN1KMT2AMETAP2 | |
| SCHEMBL9764588 | 0.77 | TSHR (0.40) | ALDH1A1TSHRTDP1KMT2ANPSR1 | |
| SCHEMBL6564298 | 0.77 | L3MBTL1 (0.42) | ALDH1A1TSHRKMT2ANPSR1L3MBTL1 | |
| SCHEMBL8330297 | 0.77 | METAP2 (0.46) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL21073906 | 0.76 | TDP1 (0.55) | ALDH1A1TSHRTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1982000822-A1 | SUBSTITUTED OXIRANECARBOXYLIC ACIDS,THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | EISTETTER K | 1982-03-18 | — | — | WO | disclosed |