Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 3/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11218914 | 0.76 | LMNA (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL11218647 | 0.74 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL19932178 | 0.74 | CXCR2 (0.48) | CXCR2CXCR1MEN1KMT2ALMNA | |
| SCHEMBL19927416 | 0.73 | CXCR2 (0.57) | CXCR2CXCR1MEN1KMT2AMAPT | |
| SCHEMBL9024697 | 0.71 | L3MBTL1 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL9463834 | 0.70 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL11081946 | 0.69 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL8410380 | 0.68 | CXCR2 (0.55) | CXCR2CXCR1ALDH1A1MEN1KMT2A | |
| SCHEMBL9760575 | 0.68 | KCNMA1 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL7135205 | 0.68 | EPHX2 (0.36) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023257-B1 | Dichloro-hydroxyethylamino phenols, process for their production, their use and hair dyeing compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1982-06-30 | — | — | EP | claimed |
| EP-0023257-A1 | Dichloro-hydroxyethylamino phenols, process for their production, their use and hair dyeing compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-02-04 | — | — | EP | claimed |
| EP-0023257-B1 | Dichloro-hydroxyethylamino phenols, process for their production, their use and hair dyeing compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1982-06-30 | — | — | EP | disclosed |
| EP-0023257-A1 | Dichloro-hydroxyethylamino phenols, process for their production, their use and hair dyeing compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-02-04 | — | — | EP | disclosed |