Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.57 |
| ▸ | DRD4 | P21917 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL11227420 | 0.94 | MAPK14 (0.53) | DRD2DRD4DRD3MAPK14HTR1A | |
| SCHEMBL11231626 | 0.88 | DRD2 (0.46) | DRD2DRD4DRD3MAPK14HTR1A | |
| SCHEMBL31530785 | 0.85 | HTR1A (0.66) | DRD2HTR1AHTR2AHTTACHE | |
| SCHEMBL2783395 | 0.85 | HTR1A (0.66) | DRD2HTR1AHTR2AHTTACHE | |
| SCHEMBL11228631 | 0.84 | KDM4E (0.44) | DRD2DRD4DRD3GAAADRB1 | |
| SCHEMBL11233776 | 0.81 | ADRB1 (0.41) | HTR2AADRB1HTR6 | |
| SCHEMBL11233825 | 0.81 | CREBBP (0.43) | DRD2DRD4DRD3HTR1APIK3CA | |
| SCHEMBL11229113 | 0.81 | ADRB1 (0.40) | DRD2DRD4DRD3HTR1APIK3CA | |
| Phosphoric Acid SCHEMBL11224415 | 0.78 | KDM4E (0.40) | ADRB1HTR6 | |
| SCHEMBL11228410 | 0.78 | HTR2A (0.54) | HTR2AADRB1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332808-A | Dopaminergically stimulating 4-substituted indoles | ROUSSEL UCLAF (FR) | 1982-06-01 | — | — | US | disclosed |