Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11228631 | 0.84 | KDM4E (0.44) | ADRB1HTR6DRD2DRD4DRD3 | |
| SCHEMBL11233776 | 0.81 | ADRB1 (0.41) | ADRB1HTR6 | |
| SCHEMBL10677773 | 0.81 | HTR1A (0.53) | HTR6ADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL11220044 | 0.81 | DRD2 (0.57) | ADRB1HTR6DRD2DRD4DRD3 | |
| SCHEMBL11233825 | 0.81 | CREBBP (0.43) | ADRB1HTR6DRD2DRD4DRD3 | |
| SCHEMBL11231626 | 0.79 | DRD2 (0.46) | ADRB1HTR6DRD2DRD4DRD3 | |
| Phosphoric Acid SCHEMBL11224415 | 0.78 | KDM4E (0.40) | ADRB1HTR6 | |
| SCHEMBL11228410 | 0.78 | HTR2A (0.54) | ADRB1HTR6PIK3CD | |
| Oxalic Acid SCHEMBL11227420 | 0.76 | MAPK14 (0.53) | DRD2DRD4DRD3HTR1APIK3CA | |
| Phosphoric Acid SCHEMBL11228105 | 0.75 | CREBBP (0.44) | ADRB1HTR6ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332808-A | Dopaminergically stimulating 4-substituted indoles | ROUSSEL UCLAF (FR) | 1982-06-01 | — | — | US | disclosed |