Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11228631 | 0.90 | KDM4E (0.44) | ADRB1HTR6 | |
| SCHEMBL11231626 | 0.84 | DRD2 (0.46) | ADRB1HTR6HTR2A | |
| SCHEMBL11228410 | 0.84 | HTR2A (0.54) | ADRB1HTR6HTR2A | |
| Phosphoric Acid SCHEMBL11224415 | 0.83 | KDM4E (0.40) | ADRB1HTR6 | |
| SCHEMBL11229113 | 0.81 | ADRB1 (0.40) | ADRB1HTR6 | |
| SCHEMBL11233825 | 0.81 | CREBBP (0.43) | ADRB1HTR6 | |
| SCHEMBL11220044 | 0.81 | DRD2 (0.57) | ADRB1HTR6HTR2A | |
| SCHEMBL10671532 | 0.80 | HTR1A (0.59) | HTR6HTR2A | |
| SCHEMBL10933661 | 0.77 | HTR2A (0.46) | HTR2A | |
| Oxalic Acid SCHEMBL11227420 | 0.77 | MAPK14 (0.53) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332808-A | Dopaminergically stimulating 4-substituted indoles | ROUSSEL UCLAF (FR) | 1982-06-01 | — | — | US | claimed |
| EP-0021924-A2 | Indole derivatives, process for their preparation, their use as medicines and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1981-01-07 | — | — | EP | claimed |
| US-4332808-A | Dopaminergically stimulating 4-substituted indoles | ROUSSEL UCLAF (FR) | 1982-06-01 | — | — | US | disclosed |