Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MAP2K4 | P45985 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.45 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL956608 | 0.89 | PRKAG1 (0.55) | KDM4EMAP2K4MAPK1MAPK6PRKAG1 | |
| SCHEMBL11015155 | 0.81 | JAK2 (0.51) | PRKAG1PRKAA1PRKAB1HAO1PDPK1 | |
| SCHEMBL4932564 | 0.81 | PRKAG1 (0.45) | KDM4EMAP2K4MAPK1MAPK6PRKAG1 | |
| SCHEMBL20839333 | 0.81 | F7 (0.47) | KDM4EMAP2K4MAPK1PRKAG1PRKAA1 | |
| SCHEMBL15253767 | 0.80 | RBP4 (0.46) | MAP2K4MAPK1MAPK6PRKAG1PRKAA1 | |
| SCHEMBL2816583 | 0.79 | MAP2K4 (0.61) | MAP2K4MAPK1MAPK6PRKAG1PRKAA1 | |
| SCHEMBL28575862 | 0.78 | NTRK1 (0.58) | MAP2K4MAPK1MAPK6MAPTRBP4 | |
| SCHEMBL591699 | 0.78 | RBP4 (0.45) | MAP2K4MAPK1MAPK6PRKAG1PRKAA1 | |
| SCHEMBL5908296 | 0.77 | KDM4E (0.57) | KDM4EMAP2K4MAPK1MAPK6ALDH1A1 | |
| SCHEMBL11165259 | 0.76 | MAP2K4 (0.44) | KDM4EMAP2K4MAPK1MAPK6HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57144264-A | — | — | None | — | — | JP | disclosed |
| JP-S57144264-A | 6-FLUORO-1,4-DIHYDRO-4-OXOCINNOLINE-3-CARBOXYLIC ACID DERIVATIVE | KANEBO LTD | 1982-09-06 | — | — | JP | disclosed |