Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011160 | 0.85 | KDM4E (0.47) | KDM4ELMNATHRBCES2CES1 | |
| SCHEMBL21895671 | 0.83 | KDM4E (0.46) | KDM4ELMNATHRBCES2CES1 | |
| SCHEMBL1243476 | 0.83 | KDM4E (0.46) | KDM4ELMNATHRBCES2CES1 | |
| SCHEMBL818204 | 0.83 | KDM4E (0.49) | KDM4ELMNATHRBALDH1A1KMT2A | |
| SCHEMBL14449130 | 0.83 | KDM4E (0.49) | KDM4ELMNATHRBALDH1A1KMT2A | |
| SCHEMBL11339493 | 0.76 | LMNA (0.46) | KDM4ELMNATHRBALDH1A1KMT2A | |
| SCHEMBL21895666 | 0.75 | CES2 (0.46) | KDM4ELMNACES2CES1ALDH1A1 | |
| SCHEMBL1748182 | 0.72 | KMO (0.57) | CES2CES1HSD11B1RORCCA1 | |
| SCHEMBL12265866 | 0.72 | KMO (0.57) | CES2CES1HSD11B1RORCCA1 | |
| SCHEMBL1748183 | 0.72 | KMO (0.57) | CES2CES1HSD11B1RORCCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57128641-A | — | — | None | — | — | JP | disclosed |
| JP-S57128641-A | 2-NORBORNENE COMPOUND | GRELAN PHARMACEUT CO LTD | 1982-08-10 | — | — | JP | disclosed |