Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818204 | 1.00 | KDM4E (0.49) | KDM4ELMNAALDH1A1KMT2ARAB9A | |
| SCHEMBL8011160 | 0.84 | KDM4E (0.47) | KDM4ELMNAALDH1A1KMT2ARAB9A | |
| SCHEMBL11220672 | 0.83 | KDM4E (0.50) | KDM4ELMNAALDH1A1KMT2ARAB9A | |
| SCHEMBL1243476 | 0.83 | KDM4E (0.46) | KDM4ELMNAALDH1A1KMT2ATHRB | |
| SCHEMBL21895671 | 0.83 | KDM4E (0.46) | KDM4ELMNAALDH1A1KMT2ATHRB | |
| SCHEMBL21895666 | 0.81 | CES2 (0.46) | KDM4ELMNAALDH1A1KMT2ARAB9A | |
| SCHEMBL4254731 | 0.79 | KDM4E (0.44) | KDM4ELMNAALDH1A1KMT2ARAB9A | |
| SCHEMBL30430712 | 0.78 | THRB (0.61) | KDM4ELMNAALDH1A1KMT2ARAB9A | |
| SCHEMBL30337051 | 0.78 | THRB (0.61) | KDM4ELMNAALDH1A1KMT2ARAB9A | |
| SCHEMBL8523728 | 0.78 | THRB (0.61) | KDM4ELMNAALDH1A1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1815838-A1 | Solid materials obtainable by the ring-opening methathesis polymerization | 3M Innovative Properties Company (US) | 2007-08-08 | — | — | EP | disclosed |