SCHEMBL1243476

SCHEMBL1243476

Cc1ccc(C(=O)C2CC3C=CC2C3)cc1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.46
LMNA P02545 2/20 0.46
ALDH1A1 P00352 6/20 0.44
THRB P10828 1/20 0.43
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
CYP2D6 P10635 1/20 0.41
POLB P06746 1/20 0.41
HTT P42858 2/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
CYP1A2 P05177 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HSD11B1 P28845 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21895671 1.00 KDM4E (0.46) KDM4ELMNAALDH1A1THRBKMT2A
SCHEMBL8011160 0.85 KDM4E (0.47) KDM4ELMNAALDH1A1THRBKMT2A
SCHEMBL11220672 0.83 KDM4E (0.50) KDM4ELMNAALDH1A1THRBKMT2A
SCHEMBL14449130 0.83 KDM4E (0.49) KDM4ELMNAALDH1A1THRBKMT2A
SCHEMBL818204 0.83 KDM4E (0.49) KDM4ELMNAALDH1A1THRBKMT2A
Toluene SCHEMBL27618261 0.77 KDM4E (0.46) KDM4ELMNAALDH1A1THRBKMT2A
SCHEMBL10099684 0.76 ALDH1A1 (0.47) KDM4ELMNAALDH1A1THRBKMT2A
SCHEMBL21895666 0.75 CES2 (0.46) KDM4ELMNAALDH1A1KMT2AMEN1
SCHEMBL18220672 0.74 ALDH1A1 (0.51) LMNAALDH1A1KMT2AMEN1CYP2D6
SCHEMBL8402254 0.73 KDM4E (0.47) KDM4ELMNAALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138757-A1 ROCKET MOTOR CESARONI AEROSPACE INCORPORATED (US) 2026-05-21 US claimed
US-12545438-B2 Rocket motor CESARONI AEROSPACE INCORPORATED (US) 2026-02-10 US claimed
US-20240150047-A1 ROCKET MOTOR CESARONI AEROSPACE INCORPORATED (US) 2024-05-09 US claimed
US-20240011749-A1 AMMUNITION CARTRIDGE CASES CESARONI AEROSPACE INCORPORATED (US) 2024-01-11 US claimed
WO-2022216362-A2 ROCKET MOTOR CESARONI AEROSPACE INCORPORATED (US) 2022-10-13 WO claimed
WO-2022098537-A1 AMMUNITION CARTRIDGE CASES CESARONI AEROSPACE INCORPORATED (US) 2022-05-12 WO claimed
US-5071701-A Containing silane substitutes cycloolefin prepared by metathesis ring-opening polymerization B. F. GOODRICH CORPORATION (US) 1991-12-10 US claimed
US-20260138757-A1 ROCKET MOTOR CESARONI AEROSPACE INCORPORATED (US) 2026-05-21 US disclosed
US-12545438-B2 Rocket motor CESARONI AEROSPACE INCORPORATED (US) 2026-02-10 US disclosed
US-20240150047-A1 ROCKET MOTOR CESARONI AEROSPACE INCORPORATED (US) 2024-05-09 US disclosed
US-20240011749-A1 AMMUNITION CARTRIDGE CASES CESARONI AEROSPACE INCORPORATED (US) 2024-01-11 US disclosed
WO-2022216362-A2 ROCKET MOTOR CESARONI AEROSPACE INCORPORATED (US) 2022-10-13 WO disclosed
WO-2022098537-A1 AMMUNITION CARTRIDGE CASES CESARONI AEROSPACE INCORPORATED (US) 2022-05-12 WO disclosed
EP-0348852-A1 Bulk polymerized cycloolefin monomers containing microencapsulated blowing agents THE B.F. GOODRICH COMPANY (US) 1990-01-03 EP disclosed
US-4891387-A FOR REACTION INJECTION MOLDING THE B. F. GOODRICH COMPANY (US) 1990-01-02 US disclosed
EP-0336105-A2 Method for enhancing the polymerization activity of crude cycloolefin monomers for bulk polymerization THE B.F. GOODRICH COMPANY (US) 1989-10-11 EP disclosed
US-4843185-A Method for enhancing the polymerization activity of crude cycloolefin monomers for bulk polymerization THE B. F. GOODRICH COMPANY (US) 1989-06-27 US disclosed
EP-0316887-A2 Method for preparing cycloolefin copolymers with improved heat stability THE B.F. GOODRICH COMPANY (US) 1989-05-24 EP disclosed
EP-0313838-A2 Cycloolefin polymers obtained from resinous monomers THE B.F. GOODRICH COMPANY (US) 1989-05-03 EP disclosed
EP-0291970-A2 Homogeneous addition copolymers of ethylene and cycloolefin monomers and the production thereof THE B.F. GOODRICH COMPANY (US) 1988-11-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545438-B2 Rocket motor ROCK2, RHOC, DCX KDM4E 1553/4885LMNA 3204/4885ALDH1A1 4182/4885
US-20260138757-A1 ROCKET MOTOR ROCK2, RHOC, RHOT2 KDM4E 607/4885LMNA 2404/4885ALDH1A1 4116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.