Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CHAT | P28329 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11358871 | 1.00 | HDAC4 (0.48) | HDAC4MEF2DAHRRELAALOX5 | |
| SCHEMBL9335390 | 0.85 | TSHR (0.52) | HDAC4MEF2DRELAALOX5PTGS1 | |
| SCHEMBL9454625 | 0.85 | TSHR (0.52) | HDAC4MEF2DRELAALOX5PTGS1 | |
| SCHEMBL9335412 | 0.85 | TSHR (0.52) | HDAC4MEF2DRELAALOX5PTGS1 | |
| SCHEMBL15096125 | 0.82 | RELA (0.56) | AHRRELAGRIN1GRIN2BCHAT | |
| SCHEMBL9605426 | 0.82 | NFE2L2 (0.56) | RELAALOX5PTGS1PTGS2KDM1A | |
| SCHEMBL16080798 | 0.81 | PTGS1 (0.49) | AHRRELAPTGS1PTGS2KDM1A | |
| SCHEMBL17553040 | 0.81 | AHR (0.52) | AHRALOX5PTGS1PTGS2GRIN1 | |
| SCHEMBL13492793 | 0.77 | ENPP2 (0.44) | HDAC4MEF2DKDM1AHDAC1HDAC6 | |
| SCHEMBL4413617 | 0.77 | TAAR1 (0.46) | HDAC4MEF2DAHRRELAGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007576-B1 | ESTERS OF STILBENE DERIVATIVES, PROCESS FOR THEIR PREPARATION, STILBENE-ALCOHOLS AS INTERMEDIATE PRODUCTS, USE OF THE ESTERS AS INSECTICIDES | BAYER AG (DE) | 1983-11-16 | — | — | EP | disclosed |
| US-4271186-A | Stilbene compounds and insecticidal/acaricidal compositions | BAYER AKTIENGESELLSCHAFT (DE) | 1981-06-02 | — | — | US | disclosed |
| EP-0007576-A2 | Esters of stilbene derivatives, process for their preparation, stilbene-alcohols as intermediate products, use of the esters as insecticides | BAYER AG (DE) | 1980-02-06 | — | — | EP | disclosed |