Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11358871 | 0.81 | HDAC4 (0.48) | PTGS1PTGS2NFE2L2AHRKDM1A | |
| SCHEMBL11220909 | 0.81 | HDAC4 (0.48) | PTGS1PTGS2NFE2L2AHRKDM1A | |
| SCHEMBL9605426 | 0.81 | NFE2L2 (0.56) | PTGS1PTGS2NFE2L2KDM1AHDAC1 | |
| SCHEMBL9454625 | 0.81 | TSHR (0.52) | PTGS1PTGS2KDM4ENFE2L2PKM | |
| SCHEMBL9335412 | 0.81 | TSHR (0.52) | PTGS1PTGS2KDM4ENFE2L2PKM | |
| SCHEMBL9335390 | 0.81 | TSHR (0.52) | PTGS1PTGS2KDM4ENFE2L2PKM | |
| SCHEMBL25911524 | 0.76 | RELA (0.59) | PTGS1PTGS2KDM4EMAPK1NFE2L2 | |
| SCHEMBL18589848 | 0.76 | RELA (0.62) | PTGS1PTGS2KDM4EMAPK1NFE2L2 | |
| SCHEMBL12228188 | 0.75 | ENPP2 (0.42) | KDM4EPKMSMN1; SMN2ALDH1A1TYR | |
| SCHEMBL3279344 | 0.75 | HDAC4 (0.47) | KDM4EHTTSMN1; SMN2ALDH1A1TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140271470-A1 | TARGETED THERANOSTICS FOR METASTATIC PROSTATE CANCER | THE REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140271470-A1 | TARGETED THERANOSTICS FOR METASTATIC PROSTATE CANCER | KLK3, ACP3, FOLH1 | PTGS1 683/4885PTGS2 606/4885KDM4E 4234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.