Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232617 | 0.90 | CALM1 (0.51) | LDHAFFAR1ALDH1A1F2RL1MMP1 | |
| SCHEMBL6177946 | 0.88 | MMP1 (0.56) | LDHAFFAR1ALDH1A1MMP12MMP1 | |
| SCHEMBL6460737 | 0.85 | MMP12 (0.65) | LDHAFFAR1ALDH1A1F2RL1MMP12 | |
| SCHEMBL6462808 | 0.84 | FFAR1 (0.50) | LDHAFFAR1ALDH1A1F2RL1MMP12 | |
| SCHEMBL6464896 | 0.84 | FFAR1 (0.50) | LDHAFFAR1ALDH1A1F2RL1MMP12 | |
| SCHEMBL5365699 | 0.84 | S1PR2 (0.62) | LDHAFFAR1ALDH1A1F2RL1MMP12 | |
| SCHEMBL11221835 | 0.83 | LDHA (0.66) | LDHAFFAR1MMP1MMP2MMP9 | |
| SCHEMBL20137984 | 0.82 | ALDH1A1 (0.46) | LDHAFFAR1ALDH1A1F2RL1MMP12 | |
| SCHEMBL1913780 | 0.82 | ALDH1A1 (0.46) | LDHAFFAR1ALDH1A1F2RL1MMP12 | |
| SCHEMBL5613430 | 0.81 | MMP12 (0.72) | FFAR1ALDH1A1MMP12MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4345096-A | 3-/P-OXYPHENYLALKYL/GLUTARIC ACID | E. R. SQUIBB & SONS, INC. (US) | 1982-08-17 | — | — | US | disclosed |
| US-4230621-A | TRACERS, HYDROXYPHENYLGLUTARIC ACID DERIVATIVES | E. R. SQUIBB & SONS, INC. (US) | 1980-10-28 | — | — | US | disclosed |
| US-4221725-A | CHEMICAL INTERMEDIATE | E. R. SQUIBB & SONS, INC. (US) | 1980-09-09 | — | — | US | disclosed |