Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122446 | 0.90 | ALDH1A1 (0.63) | KMT2ALMNAALDH1A1CYP1A2MEN1 | |
| SCHEMBL1122313 | 0.86 | ALDH1A1 (0.52) | MAOAKMT2ALMNAALDH1A1CYP1A2 | |
| SCHEMBL1122699 | 0.86 | MAOA (0.53) | MAOAKMT2ALMNAALDH1A1CYP1A2 | |
| SCHEMBL1122684 | 0.84 | LMNA (0.54) | KMT2ALMNAALDH1A1MEN1MAPT | |
| SCHEMBL1122695 | 0.82 | PTGS2 (0.51) | KMT2ALMNAALDH1A1MEN1MAPT | |
| SCHEMBL1122683 | 0.82 | ALDH1A1 (0.48) | MAOALMNAALDH1A1CYP1A2NQO2 | |
| SCHEMBL1634613 | 0.82 | ALDH1A1 (0.47) | MAOALMNAALDH1A1CYP1A2NQO2 | |
| SCHEMBL826254 | 0.82 | ALDH1A1 (0.47) | KMT2ALMNAALDH1A1CYP1A2MEN1 | |
| SCHEMBL826253 | 0.82 | ALDH1A1 (0.47) | KMT2ALMNAALDH1A1CYP1A2MEN1 | |
| SCHEMBL828284 | 0.82 | NQO2 (0.48) | KMT2ALMNAALDH1A1MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379508-B9 | N-(ARYL)-2-ARYLETHENESULFONAMIDES AND THERAPEUTIC USES THEREOF | UNIV TEMPLE (US) | 2011-02-09 | — | — | EP | disclosed |