Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 9/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11224230 | 0.96 | CCR1 (0.42) | CCR1KCNH2NR3C2NR3C1CA2 | |
| SCHEMBL11227376 | 0.89 | CCR1 (0.34) | CCR1KCNH2NR3C2NR3C1 | |
| SCHEMBL11220558 | 0.88 | DRD2 (0.40) | CCR1KCNH2 | |
| SCHEMBL11224382 | 0.87 | HTR2A (0.37) | CCR1KCNH2 | |
| SCHEMBL11224028 | 0.86 | CCR1 (0.32) | CCR1KCNH2 | |
| SCHEMBL11231912 | 0.86 | CCR1 (0.34) | CCR1KCNH2NR3C2NR3C1CA2 | |
| SCHEMBL11235100 | 0.83 | MTNR1A (0.38) | CCR1KCNH2 | |
| SCHEMBL11227155 | 0.81 | CA2 (0.40) | CCR1KCNH2NR3C2NR3C1CA1 | |
| SCHEMBL10991101 | 0.77 | SLC6A2 (0.37) | CA1CA2 | |
| SCHEMBL11234746 | 0.77 | CA2 (0.40) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353901-A | HYPERTENSION, CONGESTIVE HEART FAILURE, ARRHYTHMIAMIGRAINE, VASOSPASTIC DISORDERS, ASTHMA | SYNTEX (U.S.A.) INC. (US) | 1982-10-12 | — | — | US | disclosed |