Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11227376 | 0.90 | CCR1 (0.34) | CCR1KCNH2DRD2LRRK2 | |
| SCHEMBL11231912 | 0.90 | CCR1 (0.34) | CCR1KCNH2DRD2 | |
| SCHEMBL11220558 | 0.87 | DRD2 (0.40) | CCR1KCNH2DRD2 | |
| SCHEMBL11223663 | 0.86 | CCR1 (0.42) | CCR1KCNH2 | |
| SCHEMBL11224230 | 0.86 | CCR1 (0.42) | CCR1KCNH2 | |
| SCHEMBL11224382 | 0.86 | HTR2A (0.37) | CCR1KCNH2DRD2LRRK2 | |
| SCHEMBL11235100 | 0.86 | MTNR1A (0.38) | CCR1KCNH2DRD2LRRK2 | |
| SCHEMBL11218554 | 0.81 | DRD2 (0.34) | DRD2LRRK2 | |
| SCHEMBL10992177 | 0.76 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL11361910 | 0.73 | LMNA (0.47) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353901-A | HYPERTENSION, CONGESTIVE HEART FAILURE, ARRHYTHMIAMIGRAINE, VASOSPASTIC DISORDERS, ASTHMA | SYNTEX (U.S.A.) INC. (US) | 1982-10-12 | — | — | US | disclosed |