Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 6/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10835548 | 0.77 | MCL1 (0.35) | MCL1PTPN1NLRP3 | |
| SCHEMBL31069844 | 0.77 | MCL1 (0.35) | MCL1PTPN1NLRP3 | |
| SCHEMBL11445424 | 0.68 | JAK3 (0.38) | MCL1PTPN1NLRP3 | |
| SCHEMBL29499442 | 0.68 | JAK3 (0.38) | MCL1PTPN1NLRP3 | |
| SCHEMBL12165652 | 0.61 | NLRP3 (0.49) | MCL1PTPN1NLRP3 | |
| SCHEMBL3333888 | 0.59 | DYRK1A (0.59) | PTPN1 | |
| SCHEMBL25169039 | 0.58 | MAPT (0.46) | MCL1PTPN1NLRP3 | |
| SCHEMBL16596110 | 0.58 | ALKBH5 (0.51) | MCL1PTPN1 | |
| SCHEMBL21889374 | 0.58 | NLRP3 (0.46) | MCL1PTPN1NLRP3 | |
| SCHEMBL3340225 | 0.58 | ALKBH5 (0.51) | MCL1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57150686-A | — | — | None | — | — | JP | disclosed |
| JP-S57150686-A | 1,3-DIAZEPINO(3,4,5-LM)-BETA-CARBOLINE DERIVATIVE AND ITS PREPARATION | TANABE SEIYAKU CO LTD | 1982-09-17 | — | — | JP | disclosed |