SCHEMBL29499442

SCHEMBL29499442

C1=Cc2nccc3c4ccccc4n(c23)C1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
JAK3 P52333 1/20 0.38
MCL1 Q07820 6/20 0.35
PTPN1 P18031 2/20 0.35
DDB1 Q16531 1/20 0.32
CRBN Q96SW2 1/20 0.32
NLRP3 Q96P20 1/20 0.31
PIM1 P11309 2/20 0.30
PIM3 Q86V86 2/20 0.30
ALKBH5 Q6P6C2 1/20 0.30
FTO Q9C0B1 1/20 0.30
PIM2 Q9P1W9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11445424 1.00 JAK3 (0.38) JAK3MCL1PTPN1DDB1CRBN
SCHEMBL11342695 0.73 JAK3 (0.38) JAK3PIM1PIM3ALKBH5FTO
SCHEMBL30690427 0.73 JAK3 (0.38) JAK3PIM1PIM3ALKBH5FTO
SCHEMBL10835548 0.69 MCL1 (0.35) MCL1PTPN1NLRP3ALKBH5FTO
SCHEMBL31069844 0.69 MCL1 (0.35) MCL1PTPN1NLRP3ALKBH5FTO
SCHEMBL11224645 0.68 MCL1 (0.34) MCL1PTPN1NLRP3
SCHEMBL31742533 0.66 PIM1 (0.41) JAK3MCL1PTPN1DDB1CRBN
SCHEMBL7670850 0.64 PTPN1 (0.41) JAK3MCL1PTPN1DDB1CRBN
SCHEMBL22955422 0.64 KDM4E (0.48) JAK3MCL1
SCHEMBL12165652 0.62 NLRP3 (0.49) MCL1PTPN1NLRP3ALKBH5FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026093905-A1 NEW SELECTIVE ERAP INHIBITOR CANTHIN-6-ONE AND USES THEREOF UNIVERSITA' DEGLI STUDI DI ROMA "LA SAPIENZA" (IT) 2026-05-07 WO disclosed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP disclosed
WO-2024258363-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES SAHIN FIKRET (TR) 2024-12-19 WO disclosed
EP-4229059-A1 3-SUBSTITUTED XANTHINE DERIVATIVES AS MRGPRX4 RECEPTOR MODULATORS Rheinische Friedrich-Wilhelms-Universität Bonn (DE) 2023-08-23 EP disclosed
CN-116582633-A Method and apparatus for providing video content of multiple view point perspectives 元平台公司 2023-08-11 CN disclosed
CN-115894507-A Method for synthesizing (+) -canna oensis alkali and application thereof 昆明医科大学 2023-04-04 CN disclosed
EP-4132929-A2 NOVEL NATURE-INSPIRED ANTICANCER AND ANTIBACTERIAL MOTIFS AND PHARMACEUTICAL COMPOSITION THEREOF University of Sharjah (AE) 2023-02-15 EP disclosed
CN-115397480-A Flowable fibrinogen thrombin paste 广州倍绣生物技术有限公司 2022-11-25 CN disclosed
CN-113230254-B Medicine for resisting SARS-CoV-2 and its application 广州市朝利良生物科技有限公司 2022-08-23 CN disclosed
WO-2022079245-A1 3-SUBSTITUTED XANTHINE DERIVATIVES AS MRGPRX4 RECEPTOR MODULATORS RHEINISCHE-FRIEDRICH-WILHELMS-UNIVERSITÄT BONN (DE) 2022-04-21 WO disclosed