Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 6/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.30 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31069844 | 1.00 | MCL1 (0.35) | MCL1PTPN1NLRP3ALKBH5FTO | |
| SCHEMBL11224645 | 0.77 | MCL1 (0.34) | MCL1PTPN1NLRP3 | |
| SCHEMBL4495884 | 0.73 | ALKBH5 (0.37) | ALKBH5FTO | |
| SCHEMBL29499442 | 0.69 | JAK3 (0.38) | MCL1PTPN1NLRP3ALKBH5FTO | |
| SCHEMBL11445424 | 0.69 | JAK3 (0.38) | MCL1PTPN1NLRP3ALKBH5FTO | |
| SCHEMBL4502785 | 0.65 | ALKBH5 (0.35) | ALKBH5FTO | |
| SCHEMBL12165652 | 0.62 | NLRP3 (0.49) | MCL1PTPN1NLRP3ALKBH5FTO | |
| SCHEMBL21889374 | 0.62 | NLRP3 (0.46) | MCL1PTPN1NLRP3ALKBH5FTO | |
| SCHEMBL4501446 | 0.61 | ALKBH5 (0.39) | ALKBH5FTO | |
| SCHEMBL27917641 | 0.60 | ACHE (0.43) | MCL1PTPN1ALKBH5FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228168-A | ANTI-ANOXIC ACTIVITY | TANABE SEIYAKU CO., LTD. (JP) | 1980-10-14 | — | — | US | claimed |
| US-4617305-A | ANTIISCHEMIC AGENTS; STROKES | OMNICHEM, S.A. (BE) | 1986-10-14 | — | — | US | disclosed |
| US-4503058-A | ANTIANOXIC | SYNTHELABO (FR) | 1985-03-05 | — | — | US | disclosed |
| US-4503058-A | ANTIANOXIC | SYNTHELABO (FR) | 1985-03-05 | — | — | US | disclosed |
| US-4425351-A | ANTIANOXIC | SYNTHELABO (FR) | 1984-01-10 | — | — | US | disclosed |
| US-4425351-A | ANTIANOXIC | SYNTHELABO (FR) | 1984-01-10 | — | — | US | disclosed |
| EP-0082040-A1 | 3,7a-Diazacyclohepta(j,k)fluorene derivatives, their preparation and therapeutical use | SYNTHELABO (FR) | 1983-06-22 | — | — | EP | disclosed |
| EP-0081418-A1 | Oxygen-containing 3,7a-diazacyclohepta(J,K) fluorenes, their preparation and therapeutic use | SYNTHELABO (FR) | 1983-06-15 | — | — | EP | disclosed |
| US-4367230-A | ANTIANOXIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1983-01-04 | — | — | US | disclosed |
| US-4228168-A | ANTI-ANOXIC ACTIVITY | TANABE SEIYAKU CO., LTD. (JP) | 1980-10-14 | — | — | US | disclosed |
| US-4228168-A | ANTI-ANOXIC ACTIVITY | TANABE SEIYAKU CO., LTD. (JP) | 1980-10-14 | — | — | US | disclosed |