SCHEMBL31069844

SCHEMBL31069844

C1=Cc2nccc3c4ccccc4n(c23)C=C1

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 6/20 0.35
PTPN1 P18031 2/20 0.35
NLRP3 Q96P20 1/20 0.31
ALKBH5 Q6P6C2 1/20 0.30
FTO Q9C0B1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10835548 1.00 MCL1 (0.35) MCL1PTPN1NLRP3ALKBH5FTO
SCHEMBL11224645 0.77 MCL1 (0.34) MCL1PTPN1NLRP3
SCHEMBL4495884 0.73 ALKBH5 (0.37) ALKBH5FTO
SCHEMBL29499442 0.69 JAK3 (0.38) MCL1PTPN1NLRP3ALKBH5FTO
SCHEMBL11445424 0.69 JAK3 (0.38) MCL1PTPN1NLRP3ALKBH5FTO
SCHEMBL4502785 0.65 ALKBH5 (0.35) ALKBH5FTO
SCHEMBL12165652 0.62 NLRP3 (0.49) MCL1PTPN1NLRP3ALKBH5FTO
SCHEMBL21889374 0.62 NLRP3 (0.46) MCL1PTPN1NLRP3ALKBH5FTO
SCHEMBL4501446 0.61 ALKBH5 (0.39) ALKBH5FTO
SCHEMBL27917641 0.60 ACHE (0.43) MCL1PTPN1ALKBH5FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118515667-A Method for synthesizing 3,7A-diazacyclohepta [ jk ] fluorene derivative 山西医科大学 2024-08-20 CN claimed
CN-118515667-A Method for synthesizing 3,7A-diazacyclohepta [ jk ] fluorene derivative 山西医科大学 2024-08-20 CN disclosed
CN-118515667-A Method for synthesizing 3,7A-diazacyclohepta [ jk ] fluorene derivative 山西医科大学 2024-08-20 CN disclosed
CN-118515667-A Method for synthesizing 3,7A-diazacyclohepta [ jk ] fluorene derivative 山西医科大学 2024-08-20 CN disclosed