Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29612036 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2SIGMAR1NOTUMALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL5428326 | 0.98 | SMN1; SMN2 (0.52) | SMN1; SMN2SIGMAR1NOTUMALDH1A1MEN1 | |
| SCHEMBL1447375 | 0.94 | TSHR (0.48) | SMN1; SMN2SIGMAR1NOTUMALDH1A1MEN1 | |
| SCHEMBL1448243 | 0.92 | AVPR2 (0.46) | SMN1; SMN2SIGMAR1NOTUMALDH1A1MEN1 | |
| SCHEMBL9837085 | 0.92 | AVPR2 (0.46) | SMN1; SMN2SIGMAR1NOTUMALDH1A1MEN1 | |
| SCHEMBL29625280 | 0.86 | MEN1 (0.54) | SMN1; SMN2SIGMAR1NOTUMALDH1A1MEN1 | |
| SCHEMBL112247 | 0.86 | MEN1 (0.54) | SMN1; SMN2SIGMAR1NOTUMALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL1163794 | 0.84 | MEN1 (0.52) | SIGMAR1NOTUMALDH1A1MEN1KMT2A | |
| Propane SCHEMBL6216652 | 0.79 | ALDH1A1 (0.52) | SIGMAR1NOTUMALDH1A1MEN1KMT2A | |
| SCHEMBL5739994 | 0.78 | DRD2 (0.53) | SIGMAR1NOTUMALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150141877-A1 | LED AND SHOCKWAVE THERAPY FOR TATTOO REMOVAL | INREXREM INC. (US) | 2015-05-21 | — | — | US | claimed |
| US-20140276246-A1 | SYSTEM AND METHOD FOR TATTOO REMOVAL | InrexRem | 2014-09-18 | — | — | US | claimed |
| CN-103987694-A | Coupler with 7-amino-1,2,3,4-tetrahydroquinoline structure, dyeing composition comprising same, processes and uses | OREAL | 2014-08-13 | — | — | CN | claimed |
| US-7375180-B2 | Methods and compositions related to IRM compounds and Toll-like receptor 8 | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-05-20 | — | — | US | claimed |
| EP-1884513-A1 | PYRAZOLE COMPOUND AND THERAPEUTIC AGENT FOR DIABETES COMPRISING THE SAME | Japan Tobacco, Inc. (JP) | 2008-02-06 | — | — | EP | claimed |
| EP-1592302-A4 | METHODS AND COMPOSITIONS RELATED TO IRM COMPOUNDS AND TOLL-LIKE RECEPTOR 8 | 3M INNOVATIVE PROPERTIES CO (US) | 2007-04-25 | — | — | EP | claimed |
| US-7179253-B2 | Method of tattoo removal | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-02-20 | — | — | US | claimed |
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | claimed |
| WO-2006130399-A2 | THERAPEUTIC COMBINATIONS AND METHODS INCLUDING IRM COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-12-07 | — | — | WO | claimed |
| EP-1603476-A2 | METHOD OF TATTOO REMOVAL | 3M Innovative Properties Company (US) | 2005-12-14 | — | — | EP | claimed |
| EP-1592302-A2 | METHODS AND COMPOSITIONS RELATED TO IRM COMPOUNDS AND TOLL-LIKE RECEPTOR 8 | 3M Innovative Properties Company (US) | 2005-11-09 | — | — | EP | claimed |
| US-20050226878-A1 | Therapeutic combinations and methods including IRM compounds | 3M INNOVATIVE PROPERTIES COMPANY | 2005-10-13 | — | — | US | claimed |
| CN-1610550-A | Pharmaceutical formulations comprising an immune response modifier | 3M INNOVATIVE PROPERTIES CO (US) | 2005-04-27 | — | — | CN | claimed |
| WO-2004080292-A2 | METHOD OF TATTOO REMOVAL | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-09-23 | — | — | WO | claimed |
| US-20040181211-A1 | Method of tattoo removal | 3M INNOVATIVE PROPERTIES COMPANY | 2004-09-16 | — | — | US | claimed |
| WO-2004071459-A2 | METHODS AND COMPOSITIONS RELATED TO IRM COMPOUNDS AND TOLL-LIKE RECEPTOR 8 | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-08-26 | — | — | WO | claimed |
| US-20040162309-A1 | Methods and compositions related to IRM compounds and toll-like receptor 8 | 3M INNOVATIVE PROPERTIES COMPANY | 2004-08-19 | — | — | US | claimed |
| JP-58134642-A | — | — | None | — | — | JP | disclosed |
| JP-S58134642-A | ELECTROPHOTOGRAPHIC RECEPTOR | KONISHIROKU PHOTO IND CO LTD | 1983-08-10 | — | — | JP | disclosed |
| US-4051099-A | ISOINDOLES | CIBA-GEIGY CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | PYGL, GYS2, AGL | SMN1; SMN2 4705/4885SIGMAR1 1156/4885NOTUM 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.