Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11327056 | 0.95 | POLB (0.43) | POLBLMNATSHRMAPK1HTT | |
| SCHEMBL11324734 | 0.89 | PDE6D (0.45) | HDAC1 | |
| SCHEMBL11326306 | 0.87 | CCKBR (0.41) | HDAC6POLBLMNATSHRMAPK1 | |
| SCHEMBL11318737 | 0.85 | TMEM97 (0.42) | HDAC6LMNATSHRMAPK1HTT | |
| SCHEMBL11320266 | 0.82 | POLB (0.45) | POLBLMNATSHRMAPK1HTT | |
| SCHEMBL8029222 | 0.82 | HDAC6 (0.51) | HDAC6POLBLMNAHDAC3HDAC1 | |
| SCHEMBL11322274 | 0.81 | ALOX5 (0.44) | POLBLMNATSHRMAPK1HTT | |
| SCHEMBL11224743 | 0.81 | POLB (0.40) | HDAC6POLBLMNATSHRMAPK1 | |
| SCHEMBL11326595 | 0.78 | TRPM8 (0.47) | NPSR1MAPK14TRPM8GPR139TBXAS1 | |
| SCHEMBL11312650 | 0.77 | KIF11 (0.41) | POLBLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250183-A | GASTOINTESTINAL DISORDERS; DISEASES OF THE PANCREAS, GALL BLADDER, AND LIVER | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-02-10 | — | — | US | disclosed |
| US-4245059-A | GOOD ADHESION TO COATINGS, SUSCEPTIBLE TO DECORATIVE FINISHES | MITSUBISHI RAYON CO., LTD. (JP) | 1981-01-13 | — | — | US | disclosed |
| US-3997627-A | Polyester molding compositions containing hydroxy containing vinyl monomers and coated molded articles thereof | MITSUBISHI RAYON CO., LTD. (JA) | 1976-12-14 | — | — | US | disclosed |