Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11226270 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HPGDARABCC9ABCC8 | |
| SCHEMBL8518923 | 0.80 | ALDH1A1 (0.55) | ALDH1A1ARABCC9ABCC8KCNJ11 | |
| SCHEMBL7738811 | 0.78 | NPC1 (0.58) | ALDH1A1HPGD | |
| SCHEMBL9760688 | 0.72 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL11658598 | 0.72 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL8519769 | 0.72 | ALDH1A1 (0.54) | ALDH1A1ARABCC9ABCC8KCNJ11 | |
| SCHEMBL10974445 | 0.71 | ALDH1A1 (0.50) | ALDH1A1ARABCC9ABCC8KCNJ11 | |
| SCHEMBL14087515 | 0.70 | ALDH1A1 (0.55) | ALDH1A1AR | |
| SCHEMBL10898040 | 0.68 | HPGD (0.47) | ALDH1A1HPGD | |
| SCHEMBL7515733 | 0.68 | ABCC9 (0.68) | ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002309-B1 | ACYLANILIDES, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL AND VETERINARY COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-01 | — | — | EP | disclosed |