Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.40 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6033285 | 0.75 | GABRP (0.49) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL29209595 | 0.69 | SMN1; SMN2 (0.50) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL2711407 | 0.69 | SMN1; SMN2 (0.50) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL6031607 | 0.67 | MAPT (0.52) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL22581437 | 0.65 | TDP1 (0.45) | ALDH1A1RAB9AMAPTKMT2AMAPK1 | |
| SCHEMBL20143373 | 0.65 | ALDH1A1 (0.62) | ALDH1A1RAB9AMAPTGAAKMT2A | |
| SCHEMBL11348732 | 0.64 | MAPT (0.53) | ALDH1A1RAB9AMAPTGAAKDM4E | |
| SCHEMBL11352288 | 0.64 | ELOVL1 (0.46) | ALDH1A1RAB9AMAPTKMT2AMAPK1 | |
| SCHEMBL9363349 | 0.62 | POLB (0.73) | ALDH1A1RAB9AGAAKMT2AMAPK1 | |
| SCHEMBL22581315 | 0.62 | TDP1 (0.41) | ALDH1A1RAB9AMAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321372-A | Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides | PFIZER INC. (US) | 1982-03-23 | — | — | US | disclosed |