Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123030 | 1.00 | GAA (0.35) | GAAPOLBHTR2CCES1ALDH1A1 | |
| SCHEMBL3350738 | 1.00 | GAA (0.35) | GAAPOLBHTR2CCES1ALDH1A1 | |
| SCHEMBL9422808 | 0.75 | POLB (0.36) | GAAPOLB | |
| SCHEMBL8792481 | 0.71 | KDM4E (0.38) | GAAPOLBALDH1A1MAPTLMNA | |
| SCHEMBL16886968 | 0.67 | HTR2C (0.39) | HTR2CCES1ALDH1A1MAPTLMNA | |
| SCHEMBL15606100 | 0.67 | HTR2C (0.39) | HTR2CCES1ALDH1A1MAPTLMNA | |
| SCHEMBL13852722 | 0.67 | DRD2 (0.33) | GAAPOLB | |
| SCHEMBL16892359 | 0.66 | CA2 (0.43) | LMNA | |
| SCHEMBL15384943 | 0.66 | CA2 (0.56) | LMNA | |
| SCHEMBL2307894 | 0.66 | GAA (0.55) | GAAPOLBHTR2CCES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828198-B1 | METHOD FOR SEPARATING OF OPTICALLY PURE THIOPHENE COMPOUNDS USING SIMULATED MOVING BED CHROMATOGRAPHY | SK HOLDINGS CO LTD (KR) | 2011-02-09 | — | — | EP | disclosed |
| US-7767832-B2 | Method for separating of optically pure thiophene compounds using simulated moving bed chromatography | SK HOLDINGS CO., LTD. (KR) | 2010-08-03 | — | — | US | disclosed |
| EP-2128161-A1 | Process for obtaining 4-hydroxy-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-7,7-dioxide and its enantiomers, and applications thereof | Ragactives, S.L. (ES) | 2009-12-02 | — | — | EP | disclosed |
| US-20090234140-A1 | METHOD FOR SEPARATING OF OPTICALLY PURE THIOPHENE COMPOUNDS USING SIMULATED MOVING BED CHROMATOGRAPHY | SK CORPORATION (KR) | 2009-09-17 | — | — | US | disclosed |
| EP-1828198-A4 | METHOD FOR SEPARATING OF OPTICALLY PURE THIOPHENE COMPOUNDS USING SIMULATED MOVING BED CHROMATOGRAPHY | SK HOLDINGS CO LTD (KR) | 2008-12-03 | — | — | EP | disclosed |
| EP-1828198-A1 | METHOD FOR SEPARATING OF OPTICALLY PURE THIOPHENE COMPOUNDS USING SIMULATED MOVING BED CHROMATOGRAPHY | SK Corporation (KR) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006068333-A1 | METHOD FOR SEPARATING OF OPTICALLY PURE THIOPHENE COMPOUNDS USING SIMULATED MOVING BED CHROMATOGRAPHY | SK CORPORATION (KR) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234140-A1 | METHOD FOR SEPARATING OF OPTICALLY PURE THIOPHENE COMPOUNDS USING SIMULATED MOVING BED CHROMATOGRAPHY | QDPR, DDT, THOP1 | GAA 869/4885POLB 1108/4885HTR2C 637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.