Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11226456 | 0.83 | ALDH1A1 (0.50) | MAPTALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL5704376 | 0.82 | KMT2A (0.54) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL27727201 | 0.82 | MAPT (0.52) | PDE7AAPPKMT2AMAPTHPGD | |
| SCHEMBL31090820 | 0.81 | PDE7A (0.73) | PDE7AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL2020498 | 0.81 | PDE7A (0.73) | PDE7AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27633813 | 0.78 | SMN1; SMN2 (0.54) | PDE7AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9062019 | 0.78 | LMNA (0.49) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL7683695 | 0.77 | KDM4E (0.52) | PDE7AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11227633 | 0.76 | MAPT (0.45) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL7683703 | 0.76 | ALDH1A1 (0.49) | PDE7AAPPMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363905-A | PHASE TRANSFER CATALYST | GENERAL ELECTRIC COMPANY (US) | 1982-12-14 | — | — | US | disclosed |
| US-4316981-A | Polycarbonate transesterification | GENERAL ELECTRIC COMPANY (US) | 1982-02-23 | — | — | US | disclosed |