Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12121503 | 0.81 | PLK1 (0.47) | MAPTALPGALDH1A1NPSR1LMNA | |
| SCHEMBL11226456 | 0.79 | ALDH1A1 (0.50) | MAPTALDH1A1LMNANPC1RAB9A | |
| SCHEMBL11225857 | 0.78 | ALDH1A1 (0.51) | MAPTALPGALDH1A1NPSR1LMNA | |
| SCHEMBL247374 | 0.78 | THRB (0.56) | ALDH1A1 | |
| SCHEMBL11653500 | 0.76 | MAPT (0.44) | MAPTALPGALDH1A1NPSR1LMNA | |
| SCHEMBL11226152 | 0.76 | PDE7A (0.50) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL5704376 | 0.75 | KMT2A (0.54) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL248390 | 0.74 | THRB (0.63) | MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9062019 | 0.74 | LMNA (0.49) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11228541 | 0.73 | ALOX5 (0.45) | MAPTALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363905-A | PHASE TRANSFER CATALYST | GENERAL ELECTRIC COMPANY (US) | 1982-12-14 | — | — | US | disclosed |
| US-4316981-A | Polycarbonate transesterification | GENERAL ELECTRIC COMPANY (US) | 1982-02-23 | — | — | US | disclosed |