SCHEMBL1122691

SCHEMBL1122691

COc1cc(OC)c(N)c(OC)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 1/20 0.55
TUBB P07437 1/20 0.55
TUBA3C P0DPH7 1/20 0.55
TUBA1B P68363 1/20 0.55
TUBA4A P68366 1/20 0.55
TUBB4B P68371 1/20 0.55
TUBB3 Q13509 1/20 0.55
TUBB2A Q13885 1/20 0.55
TUBB8 Q3ZCM7 1/20 0.55
TUBA3E Q6PEY2 1/20 0.55
TUBA1A Q71U36 1/20 0.55
TUBA1C Q9BQE3 1/20 0.55
TUBB6 Q9BUF5 1/20 0.55
TUBB2B Q9BVA1 1/20 0.55
TUBB1 Q9H4B7 1/20 0.55
ALDH1A1 P00352 7/20 0.54
CYP3A4 P08684 5/20 0.54
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5265528 0.97 ALDH1A1 (0.58) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL2841590 0.87 ALDH1A1 (0.54) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL5981479 0.86 ALDH1A1 (0.46) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL7479301 0.85 MAPT (0.57) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL16372580 0.85 TUBB4A (0.49) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Water SCHEMBL28069713 0.84 TUBB4A (0.47) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL8064697 0.84 TUBB4A (0.47) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL13862076 0.84 TAAR1 (0.48) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL1426410 0.84 TUBB4A (0.47) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Hydrochloric Acid SCHEMBL3006680 0.82 ALDH1A1 (0.48) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110669058-A Tricyclic quinolone carboxylic acid and preparation method thereof 江西农业大学 2020-01-10 CN claimed
WO-2019063611-A1 OXIDATION DYEING PROCESS USING A COUPLER AND A PEROXYGENATED SALT AS OXIDIZING AGENT L'OREAL (FR) 2019-04-04 WO claimed
EP-1066269-B1 TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVES FOR TREATMENT OF HIV INFECTIONS JANSSEN PHARMACEUTICA NV (BE) 2005-05-11 EP claimed
US-20020115668-A1 Trisubstituted 1,3,5-triazine derivatives DAEYAERT FREDERIK FRANS DESIRE (BE) 2002-08-22 US claimed
EP-1066269-A1 TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVES FOR TREATMENT OF HIV INFECTIONS JANSSEN PHARMACEUTICA N.V. (BE) 2001-01-10 EP claimed
US-6150360-A ADMINISTERING TO A PATIENT SUFFERING FROM HUMAN IMMUNODEFICIENCY VIRUS INFECTION A TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVE JANSSEN PHARMACEUTICA N.V. (BE) 2000-11-21 US claimed
WO-1999050256-A1 TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVES FOR TREATMENT OF HIV INFECTIONS JANSSEN PHARMACEUTICA N.V. (BE) 1999-10-07 WO claimed
EP-0283742-B1 FATTY ACID AMIDES AS INHIBITORS OF ACYL-COA: CHOLESTEROL ACYLTRANSFERASE WARNER-LAMBERT COMPANY (US) 1993-05-26 EP claimed
EP-4452203-B1 PROCESS FOR DYEING KERATIN FIBRES USING A COSMETIC COMPOSITION COMPRISING PROPANE-1,3-DIOL AND A DYEING COMPOSITION OREAL (FR) 2025-12-24 EP disclosed
US-20250082555-A1 PROCESS FOR DYEING KERATIN FIBRES USING A COSMETIC COMPOSITION COMPRISING PROPANE-1,3-DIOL AND A DYEING COMPOSITION L'OREAL (FR) 2025-03-13 US disclosed
CN-117342964-B Synthesis method of N, N' -bis (2, 4, 6-trimethoxyphenyl) oxamide 济南国鼎医药科技有限公司 2024-12-10 CN disclosed
EP-4452203-A1 PROCESS FOR DYEING KERATIN FIBRES USING A COSMETIC COMPOSITION COMPRISING PROPANE-1,3-DIOL AND A DYEING COMPOSITION L'OREAL (FR) 2024-10-30 EP disclosed
CN-118367143-A Composite binder and application thereof 上海兰钧新能源科技有限公司 2024-07-19 CN disclosed
EP-3786196-B1 METHOD FOR PRODUCING COPOLYMER OF ALLYL MONOMER HAVING POLAR GROUP UNIV TOKYO (JP) 2024-05-08 EP disclosed
EP-0252524-A2 Aryl- and aralkylamide- derivatives of Omega- (substituted-phenyloxy)-alkanoic acids as inhibitors of acyl-coa: cholesterol acyltransferase and pharmaceuticals containing them WARNER-LAMBERT COMPANY (US) 1988-01-13 EP disclosed
EP-0242610-A1 Substituted anilides of oleic, linoleic or linolenic acid as inhibitors of acyl-coa: cholesterol acyltransferase WARNER-LAMBERT COMPANY (US) 1987-10-28 EP disclosed
US-4612376-A Substituted-3,4-dihydro-4-(2,4,6-trimethoxyphenylimino)-2(1H)-pyrimidones useful as cardiotonic, antihypertensive, cerebrovascular vasodilator and anti-platelet agent FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-09-16 US disclosed
EP-0156514-A2 Photoconductive devices containing perylene dye compositions XEROX CORPORATION (US) 1985-10-02 EP disclosed
US-4514482-A DIAMINE HOLE TRANSPORT LAYER;XEROGRAPHY XEROX CORPORATION (US) 1985-04-30 US disclosed
EP-0123402-A2 Pyrimidine derivatives, preparation thereof and use thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-10-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115668-A1 Trisubstituted 1,3,5-triazine derivatives XDH, CCR5, CXCR1 TUBB4A 4429/4885TUBB 4306/4885TUBA3C 2975/4885
US-20250082555-A1 PROCESS FOR DYEING KERATIN FIBRES USING A COSMETIC COMPOSITION COMPRISING PROPANE-1,3-DIOL AND A DYEING COMPOSITION KRT18, DSG1, DSC1 TUBB4A 483/4885TUBB 198/4885TUBA3C 211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.