Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 10/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 8/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 15/20 | 0.65 |
| ▸ | ADRA1D | P25100 | 13/20 | 0.65 |
| ▸ | ADRA1B | P35368 | 12/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 8/20 | 0.65 |
| ▸ | MAOA | P21397 | 2/20 | 0.65 |
| ▸ | MAOB | P27338 | 2/20 | 0.65 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11227435 | 0.98 | ADRA2C (0.97) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL6366752 | 0.88 | ADRA2B (0.79) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL4209729 | 0.88 | ADRA2C (0.78) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL9654151 | 0.87 | ADRA2C (0.76) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL10965126 | 0.85 | ADRA2C (0.74) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL9654750 | 0.84 | ADRA2C (0.72) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL9654125 | 0.84 | ADRA2C (0.72) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL11232303 | 0.82 | ADRA2C (0.68) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL11227694 | 0.82 | ADRA2C (0.69) | ADRA2CADRA2BADRA1AADRA1DADRA1B | |
| SCHEMBL11157947 | 0.80 | ADRA2C (0.74) | ADRA2CADRA2BADRA1AADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343810-A | Method of inhibiting sickling of sickle erythrocytes using 2-((haloanilino)methyl)-2-imidazolines | THE DOW CHEMICAL COMPANY (US) | 1982-08-10 | — | — | US | claimed |
| US-4343810-A | Method of inhibiting sickling of sickle erythrocytes using 2-((haloanilino)methyl)-2-imidazolines | THE DOW CHEMICAL COMPANY (US) | 1982-08-10 | — | — | US | disclosed |