SCHEMBL11228033

SCHEMBL11228033

CN(CC(=O)OCCO)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NLRP3 Q96P20 1/20 0.41
ALDH1A1 P00352 3/20 0.41
RECQL P46063 1/20 0.41
CHRNB2 P17787 1/20 0.41
CHRNB4 P30926 1/20 0.41
CHRNA3 P32297 1/20 0.41
CHRNA4 P43681 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
GAA P10253 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
LTA4H P09960 1/20 0.39
CA12 O43570 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
GLA P06280 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2400238 0.85 SMN1; SMN2 (0.47) KMT2AALDH1A1RECQLCHRNB2CHRNB4
SCHEMBL557889 0.84 SMN1; SMN2 (0.55) MEN1KMT2AALDH1A1GAASMN1; SMN2
Hydrochloric Acid SCHEMBL7150239 0.83 SMN1; SMN2 (0.54) MEN1KMT2AALDH1A1GAASMN1; SMN2
SCHEMBL5345206 0.80 POLB (0.44) MEN1KMT2ANLRP3ALDH1A1RXFP1
SCHEMBL13603875 0.80 TDP1 (0.44) ALDH1A1RECQLTDP1GAASMN1; SMN2
Hydrochloric Acid SCHEMBL8159357 0.79 POLB (0.43) MEN1KMT2ANLRP3ALDH1A1RXFP1
SCHEMBL18180860 0.79 KMT2A (0.43) MEN1KMT2ANLRP3ALDH1A1L3MBTL1
SCHEMBL10785219 0.77 TDP1 (0.50) MEN1KMT2ANLRP3ALDH1A1TDP1
SCHEMBL28080593 0.77 CHRNB2 (0.65) MEN1KMT2AALDH1A1CHRNB2CHRNB4
SCHEMBL12088089 0.76 MTNR1A (0.42) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4310512-A Derivatives of acetic and propionic acids, compositions containing same and use as malodor counteractants BUSH BOAKE ALLEN INC. (US) 1982-01-12 US disclosed