Sugi Predict

Sugi Predict / Compounds / SCHEMBL5345206

SCHEMBL5345206

SCHEMBL5345206

COC(=O)CN(C)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ NLRP3 Q96P20 1/20 0.44
▸ ALDH1A1 P00352 4/20 0.44
▸ MAPK1 P28482 1/20 0.44
▸ NR1I2 O75469 1/20 0.43
▸ HTT P42858 1/20 0.42
▸ RXFP1 Q9HBX9 1/20 0.42
▸ CA12 O43570 1/20 0.42
▸ CA2 P00918 1/20 0.42
▸ CA9 Q16790 1/20 0.42
▸ TSHR P16473 3/20 0.41
▸ GLA P06280 1/20 0.41
▸ PTPN1 P18031 1/20 0.41
▸ PTPN6 P29350 1/20 0.41
▸ PTPN11 Q06124 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.40
▸ LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8159357 0.98 POLB (0.43) POLBMEN1KMT2ANLRP3ALDH1A1
SCHEMBL28709069 0.90 ALDH1A1 (0.47) POLBMEN1KMT2AALDH1A1NR1I2
SCHEMBL28710151 0.87 SMN1; SMN2 (0.51) POLBALDH1A1NR1I2HTT
SCHEMBL8911970 0.83 ALDH1A1 (0.46) POLBKMT2AALDH1A1HTTTSHR
SCHEMBL32670823 0.83 CA12 (0.42) ALDH1A1MAPK1NR1I2CA12CA2
SCHEMBL18180860 0.83 KMT2A (0.43) POLBMEN1KMT2ANLRP3ALDH1A1
SCHEMBL7437555 0.82 MTNR1A (0.49) POLBALDH1A1MAPK1NR1I2TSHR
SCHEMBL8627738 0.82 POLB (0.46) POLBMEN1KMT2AALDH1A1MAPK1
SCHEMBL5004063 0.81 ALDH1A1 (0.46) POLBALDH1A1TSHR
SCHEMBL10785219 0.81 TDP1 (0.50) MEN1KMT2ANLRP3ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4582424-A2 1,2-NAPHTHOQUINONE DERIVATIVE AND METHOD FOR PREPARING SAME Yungjin Pharm. Co., Ltd. (KR) 2025-07-09 — — EP disclosed
EP-3091003-B1 1,2-NAPHTHOQUINONE DERIVATIVE AND METHOD FOR PREPARING SAME YUNGJIN PHARMACEUTICAL CO LTD (KR) 2025-06-04 — — EP disclosed
CN-117736104-A Method for synthesizing butanedicarboxylate derivative by visible light catalysis 常州大学 2024-03-22 — — CN disclosed
US-20210219551-A1 Compositions for Inhibition of Insect Sensing VANDERBILT UNIVERSITY 2021-07-22 — — US disclosed
CN-112300078-A 1, 2-naphthoquinone derivative and preparation method thereof 永进药品工业株式会社 2021-02-02 — — CN disclosed
CN-105992759-B 1, 2-naphthoquinone derivative and preparation method thereof 永进药品工业株式会社 2020-10-30 — — CN disclosed
US-10813355-B2 Compositions for inhibition of insect sensing VANDERBILT UNIVERSITY (US) 2020-10-27 — — US disclosed
US-20190075798-A1 Compositions for Inhibition of Insect Sensing VANDERBILT UNIVERSITY 2019-03-14 — — US disclosed
US-9975883-B2 1,2-naphthoquinone based derivative and method of preparing the same YUNGJIN PHARM. CO., LTD. (KR) 2018-05-22 — — US disclosed
US-9975883-B2 1,2-naphthoquinone based derivative and method of preparing the same YUNGJIN PHARM. CO., LTD. (KR) 2018-05-22 — — US disclosed
US-20160376258-A1 1,2-NAPHTHOQUINONE BASED DERIVATIVE AND METHOD OF PREPARING THE SAME KT&G LIFE SCIENCES CORPORATION (KR) 2016-12-29 — — US disclosed
CN-105992759-A 1, 2-naphthoquinone derivative and preparation method thereof KT&G生命科学公司 2016-10-05 — — CN disclosed
WO-2015102371-A1 1,2-NAPHTHOQUINONE DERIVATIVE AND METHOD FOR PREPARING SAME 주식회사 케이티앤지생명과학 2015-07-09 — — WO disclosed
WO-2015102371-A1 1,2-NAPHTHOQUINONE DERIVATIVE AND METHOD FOR PREPARING SAME 주식회사 케이티앤지생명과학 2015-07-09 — — WO disclosed
US-7160902-B2 Amide derivatives and methods of their use ADOLOR CORPORATION (US) 2007-01-09 — — US disclosed
US-7160902-B2 Amide derivatives and methods of their use ADOLOR CORPORATION (US) 2007-01-09 — — US disclosed
WO-2005049564-A1 AMIDE DERIVATIVES AND METHODS OF THEIR USE ADOLOR CORPORATION (US) 2005-06-02 — — WO disclosed
US-20050107355-A1 Amide derivatives and methods of their use CUBIST PHARMACEUTICALS, INC. 2005-05-19 — — US disclosed
US-5153236-A Comprising an N-aryl-alpha-amino acid and a photosensitizer such as a thixoanthone, isoalloxazine or coumarine; high sensitivity to UV and visible light; storage stability; photoresists; relief images HITACHI CHEMICAL CO., LTD. (JP) 1992-10-06 — — US disclosed
US-4310512-A Derivatives of acetic and propionic acids, compositions containing same and use as malodor counteractants BUSH BOAKE ALLEN INC. (US) 1982-01-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10813355-B2 Compositions for inhibition of insect sensing OR51E2, TRPA1, OR10J3 POLB 4832/4885MEN1 1871/4885KMT2A 4243/4885
US-20160376258-A1 1,2-NAPHTHOQUINONE BASED DERIVATIVE AND METHOD OF PREPARING THE SAME CYP2S1, GYS2, SLC5A1 POLB 2012/4885MEN1 165/4885KMT2A 3319/4885
US-20050107355-A1 Amide derivatives and methods of their use HRH2, SLC10A2, ALPI POLB 2823/4885MEN1 4308/4885KMT2A 3693/4885
US-20210219551-A1 Compositions for Inhibition of Insect Sensing OR51E2, TRPA1, OR10J3 POLB 4840/4885MEN1 1675/4885KMT2A 4200/4885
US-20190075798-A1 Compositions for Inhibition of Insect Sensing OR51E2, TRPA1, OR10J3 POLB 4832/4885MEN1 1871/4885KMT2A 4243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.