Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243827 | 1.00 | LMNA (0.49) | LMNAPPARAPPARGKMT2ASMN1; SMN2 | |
| SCHEMBL11228208 | 0.91 | ESR1 (0.45) | LMNAPPARAPPARGCES2CES1 | |
| SCHEMBL11228210 | 0.91 | ESR1 (0.45) | LMNAPPARAPPARGCES2CES1 | |
| SCHEMBL11236194 | 0.89 | CES2 (0.46) | LMNAPPARAPPARGCES2CES1 | |
| SCHEMBL11236197 | 0.89 | CES2 (0.46) | LMNAPPARAPPARGCES2CES1 | |
| SCHEMBL11241569 | 0.88 | CES2 (0.48) | LMNAPPARAPPARGCES2CES1 | |
| SCHEMBL11241565 | 0.88 | CES2 (0.48) | LMNAPPARAPPARGCES2CES1 | |
| SCHEMBL6152765 | 0.87 | LMNA (0.51) | LMNAPPARAPPARGKMT2ASMN1; SMN2 | |
| SCHEMBL11236782 | 0.87 | SMN1; SMN2 (0.44) | LMNAKMT2ASMN1; SMN2CES2CES1 | |
| SCHEMBL11236778 | 0.87 | SMN1; SMN2 (0.44) | LMNAKMT2ASMN1; SMN2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342760-A | ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1982-08-03 | — | — | US | disclosed |
| US-4264597-A | FUNGICIDES | FUJISAWA PHARMACEUTICAL CO., LTD., NO. 3, 4-CHOME, DOSHOMACHI, HIGASHI-KU, OSAKA, JAPAN | 1981-04-28 | — | — | US | disclosed |