Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235851 | 0.83 | CA2 (0.56) | MTNR1ACA2HTTMAPTTDP1 | |
| SCHEMBL11222928 | 0.83 | CA2 (0.49) | CA2HTTMAPTTDP1GAA | |
| SCHEMBL11224196 | 0.77 | CA2 (0.56) | MTNR1ACA2HTTMAPTSMN1; SMN2 | |
| SCHEMBL11230966 | 0.77 | CA2 (0.56) | CA2HTTMAPTSMN1; SMN2 | |
| SCHEMBL11232203 | 0.77 | MTNR1A (0.57) | MTNR1AMAPTTDP1GAAPOLB | |
| SCHEMBL11219443 | 0.77 | MTNR1A (0.64) | MTNR1AMAPTTDP1GAAPOLB | |
| SCHEMBL5871673 | 0.76 | HTT (0.61) | MTNR1ACA2HTTSMN1; SMN2POLB | |
| SCHEMBL17272101 | 0.75 | HTT (0.37) | CA2HTTSMN1; SMN2POLB | |
| SCHEMBL11026135 | 0.69 | CA2 (0.55) | CA2 | |
| SCHEMBL17272701 | 0.69 | CA2 (0.58) | CA2MAPTGAAHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353901-A | HYPERTENSION, CONGESTIVE HEART FAILURE, ARRHYTHMIAMIGRAINE, VASOSPASTIC DISORDERS, ASTHMA | SYNTEX (U.S.A.) INC. (US) | 1982-10-12 | — | — | US | disclosed |