SCHEMBL11228564

SCHEMBL11228564

CSc1ccc(P(=O)(Cl)Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
PLK1 P53350 1/20 0.42
GSK3B P49841 1/20 0.35
SLC6A4 P31645 3/20 0.34
NOS3 P29474 2/20 0.34
NOS1 P29475 2/20 0.34
PTGS2 P35354 2/20 0.34
FBP1 P09467 1/20 0.34
LMNA P02545 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
MAOA P21397 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12353492 0.79 HPGD (0.36) LMNATSHR
SCHEMBL23434973 0.78 ALDH1A1 (0.44) ALDH1A1PLK1GSK3BSLC6A4NOS3
SCHEMBL11697473 0.74 MEN1 (0.41) ALDH1A1TSHR
SCHEMBL83839 0.72 ALDH1A1 (0.58) ALDH1A1PLK1SLC6A4NOS3NOS1
SCHEMBL4620299 0.72 ALDH1A1 (0.42) ALDH1A1PLK1SLC6A4NOS3NOS1
SCHEMBL5966315 0.72 HPGD (0.59) ALDH1A1LMNATSHR
SCHEMBL9011105 0.71 CYP1A1 (0.41) ALDH1A1PLK1SLC6A4LMNAALOX15
SCHEMBL28138509 0.70 HPGD (0.56) ALDH1A1LMNATSHR
SCHEMBL26106467 0.69 ALDH1A1 (0.55) ALDH1A1PLK1SLC6A4NOS3NOS1
SCHEMBL918686 0.69 LMNA (0.47) ALDH1A1LMNAALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4319913-A Substituted benzazaphospholes, herbicidal compositions and the use thereof MONSANTO COMPANY (US) 1982-03-16 US disclosed
US-4046884-A N-(α-Aminoalkylidene)phosphor- and phosphonamidates, and method for controlling insects VELSICOL CHEMICAL CORPORATION (US) 1977-09-06 US disclosed