SCHEMBL11697473

SCHEMBL11697473

CSc1cccc(P(=O)(Cl)Cl)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
MAPT P10636 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP3A4 P08684 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
GRM4 Q14833 1/20 0.40
TP53 P04637 2/20 0.39
POLB P06746 1/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HPGD P15428 2/20 0.37
GAA P10253 1/20 0.37
RECQL P46063 1/20 0.36
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12353541 0.82 PGK1 (0.38) MAPTGAAALDH1A1TSHRNPSR1
SCHEMBL13534697 0.82 MEN1 (0.40) MEN1KMT2AMAPTCYP1A2CYP2D6
SCHEMBL11657502 0.77 MEN1 (0.37) MEN1KMT2AMAPTCYP1A2CYP2D6
SCHEMBL11228564 0.74 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL11222577 0.72 ACHE (0.48) MEN1KMT2ASMN1; SMN2RAB9ANPC1
SCHEMBL83808 0.72 MAPT (0.47) MEN1KMT2AMAPTCYP1A2CYP2D6
SCHEMBL13536659 0.72 IDO1 (0.41) MEN1KMT2AMAPTCYP1A2CYP2D6
SCHEMBL12353500 0.72 GRIK1 (0.41) MEN1KMT2ACYP2C9CYP3A4
SCHEMBL11223303 0.70 CES2 (0.41) MEN1KMT2ACYP1A2CYP2D6CYP3A4
SCHEMBL11248878 0.69 SMN1; SMN2 (0.40) MEN1KMT2AMAPTCYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4046884-A N-(α-Aminoalkylidene)phosphor- and phosphonamidates, and method for controlling insects VELSICOL CHEMICAL CORPORATION (US) 1977-09-06 US disclosed